Oklahoma State Cowboys (OSU)
American Football NCAAF Jack Trice Stadium Sat 31 Oct 19:00
Iowa State Cyclones
  1. Prediction
  2. SGP Picks
  3. Odds
  4. Player Props
  5. Stats
  6. Standings

Oklahoma State vs Iowa State Predictions

Best Bet

Iowa State +9.5 @ -108

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Back Iowa State to Cause OSU Problems

Iowa State are capable of staying close to Oklahoma State here, so we’ll take a chance and bet them against the spread. There’s an attractive +9.5 available which is priced at -108.

Get the complete Oklahoma State vs Iowa State betting breakdown, featuring our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Skip directly to the dedicated sections below for a comprehensive look at each pick.

Oklahoma State vs Iowa State Preview

Oklahoma State go up against Iowa State at Jack Trice Stadium, with kickoff scheduled for 19:00 on Saturday, October 31.

Oklahoma State Cowboys previous game saw them claim a 57-24 home win over Colorado Buffaloes at Boone Pickens Stadium.

Iowa State Cyclones have been defeated in back-to-back games. On the road, they recently suffered a 39-3 loss against Arizona Wildcats at Casino Del Sol Stadium.

H2H: 20-13 Iowa State Triumph in Previous H2H

Iowa State have claimed back-to-back victories over Oklahoma State. At Jack Trice Stadium they won 34-27 before winning 20-13 at Boone Pickens Stadium. The past 6 games H2H record shows that both teams have three wins.

Quarterbacks

Best Bet

Iowa State should give a good account of themselves in this college football matchup and the pick is to back them on the spread. The +9.5 looks very attractive and -108 is available.

Key stats supporting our main match prediction:

  • The +9.5 line has been covered by Iowa State in 8 of their last 10 games at home.
  • The +9.5 line has been covered by Iowa State in 16 of their last 20 games.
  • The -9.5 line hasn’t been covered by Oklahoma State in 9 of their last 10 games on the road.
  • The -9.5 line hasn’t been covered by Oklahoma State in 4 of their last 5 games on the road.
  • The +9.5 line has been covered by Iowa State in 6 consecutive games against Oklahoma State.

Recent form is always part of the equation and we combine it with team news as soon as it’s available. To deliver expert predictions, our college football handicappers also analyze the latest stats to ensure we’re working with the best information possible.

Iowa State +9.5 Probability

According to the best betting apps, there’s a 51.8% chance that our pick is settled as a winner. Our analysts think there’s a stronger chance of success and calculate the probability to be 55-60%. That means we’re regarding it as a value bet.

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If you want a viable alternative to backing Iowa State on the spread, then the Winning Margin lines could be up your street. Choose from a wide range of options.

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Iowa State +9.5 @ -108 Bet Now BetMGM logo
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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Oct 30, 01:25). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.
Published 01:25, 30 October 2026

Player Prop Picks

Top Pick: Drew Mestemaker Under 297.5 Passing Yards -114 BetMGM logo

Drew Mestemaker (Oklahoma State) is priced at -114 to record fewer than 297.5 passing yards. We’re confident he’ll fall short of the QB Passing Yards line, as the total looks too high.

Latest Drew Mestemaker Player Prop Odds

Aiden Flora Under 81.5 Rushing Yards -114 BetMGM logo

The odds for Aiden Flora (Iowa State) to finish with fewer than 81.5 rushing yards stand at -114. He is likely to fall short of the line, making this Player Rushing Yards bet an appealing option.

Latest Aiden Flora Player Prop Odds

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Same Game Parlay Pick

Spread Iowa State +9.5
Totals Under 58.5
Passing Yards Drew Mestemaker Under 297.5

Get in the game with a same game parlay. Our picks are Iowa State to cover the +9.5 spread, Under 58.5 on the total and Drew Mestemaker (Oklahoma State) to have Under 297.5 passing yards.

A same game parlay is a fantastic option for bettors who want to focus their wagering on a single football game. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Oklahoma State Oklahoma State logo 27 - 24 Iowa State logo Iowa State

A close battle could be on the cards. We’ll bet on the Cowboys to claim a 27-24 victory at huge odds and this correct score pick should hopefully be a fun one.

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Oklahoma State vs Iowa State Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

OSU Big Favorites With the Books

Oklahoma State are -345 favorites and that means a 78% chance of winning this college game according to the Moneyline betting odds with the sportsbooks. Iowa State are trading at bigger odds than their opponents and they can be backed at +275.

The spread is 9.5 and the total points line is currently 58.5. Football fans love the chance to get an alternative angle by going for a Total wager. There’s the chance to back Under 58.5 at -120.

The top sportsbooks cover every college football matchup with a great mix of game lines and team props. Whether you prefer to bet before kickoff or during the action, make sure to explore all available options.

Player Odds

Receiving Yards

Rushing Yards

Aiden Flora (Iowa State)
Over 81.5
-114
Under 81.5
-114
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Jaylen Raynor (Iowa State)
Over 16.5
-114
Under 16.5
-114
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Passing Yards

Jaylen Raynor (Iowa State)
Over 199.5
-114
Under 199.5
-114
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Live market odds and lines updated regularly. All odds subject to change. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Best Betting Offers
Jack Trice Stadium
Jack Trice Stadium

Iowa State Own Seven Victories From Previous Ten at Home

Iowa State have gone 7-3 across their last 10 home games, averaging 34.90 points scored and 20.30 points allowed.

Oklahoma State have one win and nine losses in the last 10 road games, averaging 14.70 points scored and 38.00 points allowed.

Iowa State defeated Oklahoma State 34-27 when the teams last met at Jack Trice Stadium. In 3 recent head-to-head matchups at Jack Trice Stadium, Iowa State have notched two victories, while Oklahoma State have recorded one.

Last 10 Games W-L P PF PA O58.5 U58.5
Iowa State logo Iowa State Home Stats 7-3 55.20 34.90 20.30 4 6
Oklahoma State logo Oklahoma State Away Stats 1-9 52.70 14.70 38.00 4 6
  • W-L = Wins-Losses
  • P = Avg. Points
  • PF = Avg. Points For
  • PA = Avg. Points Against
  • O58.5 = Games Over 58.5 Points
  • U58.5 = Games Under 58.5 Points
Last 5 & H2H
Team Stats

Latest regular season and playoff games stats.

Oklahoma State Cowboys logo Oklahoma State Cowboys Stats
Iowa State Cyclones logo Iowa State Cyclones Stats
Moneyline
  • 5 wins and 5 defeats in the last 10 games
  • 1 win and 9 defeats in the last 10 games on the road
Moneyline
  • 6 wins and 4 defeats in the last 10 games
  • 7 wins and 3 defeats in the last 10 home games
Point Spread
Point Spread
Total Points
Total Points
NCAAF Standings Select Season
Big 12 W L PF PA N. Pts Home Away Strk
Utah 7 0 262 102 160 5-0 2-0 7W
Arizona 6 1 253 117 136 4-0 2-1 5W
BYU 6 1 232 130 102 4-0 2-1 1L
Texas Tech 6 1 251 143 108 4-0 2-1 1L
Oklahoma State 5 2 280 166 114 4-0 1-2 1W
Houston 6 2 288 168 120 4-0 2-2 1L
Cincinnati 5 2 248 185 63 5-0 0-2 1W
Arizona State 4 3 216 209 7 3-1 1-2 1W
Baylor 4 3 204 113 91 3-1 1-2 2L
UCF 4 3 229 161 68 4-0 0-3 1W
West Virginia 5 3 287 258 29 3-2 2-1 2W
Kansas State 4 3 230 148 82 4-1 0-2 1L
Iowa State 3 4 181 169 12 3-1 0-3 2L
Kansas 3 4 217 168 49 3-2 0-2 1W
TCU 3 4 164 97 67 2-3 1-1 1L
Colorado 2 5 141 211 -70 1-2 1-3 5L

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