Syracuse vs Pittsburgh Prediction, Picks & Odds | 17 Sep 2026
College Football Betting Preview: Syracuse vs Pitt
Syracuse square off against Pitt at Acrisure Stadium, with kickoff scheduled for 19:30 on Thursday, September 17.
Bet on Pitt against the spread, with an attractive line of -9.5 that they have the upper hand against Syracuse. There are odds of -120 that are currently on offer for this selection.
Syracuse Orange were defeated in their previous game. They were beaten at home to California Golden Bears by a 21-18 scoreline at JMA Wireless Dome.
Pittsburgh Panthers made it back-to-back wins in their last game. Landing a 12-7 home victory against UCF Knights at Acrisure Stadium.
Head-to-Head Statistics
Pitt have beaten Syracuse in the last two matchups. A 41-13 victory at Acrisure Stadium was followed by a 30-13 win at JMA Wireless Dome. Pitt have won six of the past 7 games that these teams have played.
Quarterbacks
Steve Angeli
Mason Heintschel
Syracuse vs Pittsburgh Prediction & Picks
Step into Syracuse vs Pittsburgh with confidence, armed with our expert match prediction, likely scoreline, key player prop plays and a custom-built bet builder for maximum value.
Game Prediction
Pitt are available at odds of -120 when it comes to backing them against the spread in this college football battle. The -9.5 line could be covered with ease by the favorites and this looks like a value bet.
Our CFB predictions are built after tracking the latest team news and reviewing recent form. We also dive into stats, which often serve as a solid barometer for how the action might unfold.
Key Syracuse vs Pittsburgh stats:
Pitt -9.5 Probability
Looking at the latest betting odds, our pick has a 54.6% chance of winning. However, we have this figure at close to 60% based on our in-depth research. This is why we can recommend this college wager.
There’s the chance to secure bigger odds and this can be achieved by moving the line. Squeeze more juice from your spread pick by taking an alternative betting view.
Check out the most rewarding betting offers in our in-depth guide before your next wager. The best bonuses and free bets await.
Player Prop Picks
You can place a bet on Steve Angeli (Syracuse) at -114 to finish with fewer than 259.5 passing yards. There’s a strong case for choosing him to fall short of the required line in the QB Passing Yards market.
Mason Heintschel (Syracuse) is priced at -114 to record fewer than 12.5 rushing yards. He may fall short of the Player Rushing Yards line, making this prop bet a strong pick.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Get in the game with a same game parlay. Our picks are Pitt to cover the -9.5 spread, Over 51.5 on the total and Steve Angeli (Syracuse) to have Under 259.5 passing yards.
A same game parlay is a fantastic option for bettors who want to focus their wagering on a single football game. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.
Correct Score Prediction
20
-
38
Pitt
If you want to take a chance on a correct score, then the Panthers to achieve a 38-20 win could be along the right lines. There are huge odds for this particular outcome.
Syracuse vs Pittsburgh Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Pittsburgh have short betting odds and they’re overwhelming -417 favorites for this college game. This means the sportsbooks give them a 81% chance of winning. For those wanting to back Syracuse, you will find +315 about the underdogs.
The spread currently stands at 9.5 and the total points line is 51.5. The Totals offers football bettors an alternative way of getting involved. If you fancy Under 51.5, then the odds are -110.
Whether you are wagering pre-game or in-game on college football, the top betting apps let you feast on a wide range of team props and game lines. The selections are practically endless, and it’s awesome to have so many options at your fingertips.
Receiving Yards
Rushing Yards
Passing Yards
Pitt Have Dominated Recent Head-to-Head Matchups at Acrisure Stadium
Pitt have gone 6-4 across their last 10 home games, averaging 34.70 points on offense and surrendering 22.10 on defense.
Syracuse have dropped four consecutive away games. They own a 3-7 mark in their past 10 games on the road, scoring 24.00 points per contest and conceding 38.40.
The last time the teams met at Acrisure Stadium, Pitt defeated Syracuse 41-13. From 3 head-to-head games at Acrisure Stadium, Pitt have been victorious in all.
| Last 10 Games | W-L | P | PF | PA | O51.5 | U51.5 | |
|---|---|---|---|---|---|---|---|
 Pittsburgh Home Stats |
6-4 | 56.80 | 34.70 | 22.10 | 7 | 3 | |
 Syracuse Away Stats |
3-7 | 62.40 | 24.00 | 38.40 | 8 | 2 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O51.5 = Games Over 51.5 Points
- U51.5 = Games Under 51.5 Points
- NCAAF: 19/10 2025 Pittsburgh 30 Syracuse 13
- NCAAF: 25/10 2024 Syracuse 13 Pittsburgh 41
- NCAAF: 11/11 2023 Pittsburgh 13 Syracuse 28
- NCAAF: 05/11 2022 Syracuse 9 Pittsburgh 19
- NCAAF: 28/11 2021 Pittsburgh 31 Syracuse 14
- NCAAF: 19/09 2020 Syracuse 10 Pittsburgh 21
- NCAAF: 19/10 2019 Pittsburgh 27 Syracuse 20
Latest regular season and playoff games stats.
Syracuse Orange Stats
Pittsburgh Stats
- 1 win and 9 defeats in the last 10 games
- 3 wins and 7 defeats in the last 10 games on the road
- +9.5 Betting Line: Have covered the spread in 2 of the last 10 games
- +9.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road
- -9.5 Betting Line: Have covered the spread in 5 of the last 10 games
- -9.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
- Game Totals: An average of 50.60 pts in the previous 10 games
- Game Totals on the Road: An average of 62.40 pts in the previous 10 games on the road
- Over 51.5: Covered in 3 of the previous 10 games
- Over 51.5 on the Road: Covered in 8 of the previous 10 games on the road
- Team Totals: Have scored an average of 17.30 pts and allowed 33.30 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 24.00 pts and allowed 38.40 pts in the last 10 games on the road
- Game Totals: An average of 54.90 pts in the previous 10 games
- Game Totals at Home: An average of 56.80 pts in the previous 10 home games
- Over 51.5: Covered in 6 of the previous 10 games
- Over 51.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 30.40 pts and allowed 24.50 pts in the last 10 games
- Team Totals at Home: Have scored an average of 34.70 pts and allowed 22.10 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Miami
|
2 | 0 | 122 | 13 | 109 | 1-0 | 1-0 | 2W |
SMU
|
2 | 0 | 83 | 34 | 49 | 1-0 | 1-0 | 2W |
Virginia
|
2 | 0 | 93 | 11 | 82 | 2-0 | 0-0 | 2W |
California
|
1 | 1 | 45 | 63 | -18 | 0-1 | 1-0 | 1W |
Duke
|
2 | 0 | 48 | 30 | 18 | 1-0 | 1-0 | 2W |
North Carolina
|
2 | 0 | 50 | 13 | 37 | 1-0 | 1-0 | 2W |
|
Pittsburgh
|
2 | 0 | 71 | 21 | 50 | 2-0 | 0-0 | 2W |
Boston College
|
1 | 1 | 43 | 55 | -12 | 1-0 | 0-1 | 1W |
Clemson
|
1 | 1 | 32 | 58 | -26 | 1-0 | 0-1 | 1W |
Louisville
|
1 | 1 | 97 | 54 | 43 | 1-0 | 0-1 | 1W |
Georgia Tech
|
0 | 2 | 37 | 59 | -22 | 0-2 | 0-0 | 2L |
Florida State
|
1 | 1 | 58 | 44 | 14 | 1-1 | 0-0 | 1L |
NC State
|
1 | 1 | 81 | 34 | 47 | 1-0 | 0-1 | 1W |
Stanford
|
1 | 1 | 43 | 72 | -29 | 1-1 | 0-0 | 1L |
|
Syracuse
|
1 | 1 | 84 | 24 | 60 | 1-1 | 0-0 | 1L |
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