Tulane vs Duke Prediction, Picks & Odds | 05 Sep 2026

College Football Betting Preview: Tulane vs Duke

Tulane battle Duke at Wallace Wade Stadium, with kickoff scheduled for 16:30 on Saturday, September 5.

Duke and Tulane are capable of scoring more than 51.5 points. Therefore, we’re going Over the total line and expect a payout at -105.

Tulane Green Wave were beaten in their previous game and this was on the road at Vaught-Hemingway Stadium. Ole Miss Rebels claimed a 41-10 win.

Duke Blue Devils won their last game. It was a 42-39 triumph at Sun Bowl Stadium against Arizona State Sun Devils.

Head-to-Head Statistics

Tulane won the most recent matchup between these teams. A 34-27 victory was registered against Duke at Yulman Stadium.

Tulane vs Duke Prediction & Picks

Dive into our Tulane vs Duke betting tips, featuring an expert match prediction, our best correct score pick and a ready-made bet builder designed for value.

Game Prediction

We’re forecasting that the two teams will produce a significant combined points total in this college football showdown. Therefore, our pick is to take the -105 that there are Over 51.5 points.

Injuries can influence the outcome and our CFB handicappers factor that in alongside the latest form guide. We apply the same approach to the stats to build the clearest picture of how the matchup might unfold.

Key Tulane vs Duke stats:

• The 51.5 line has been covered in 7 of the last 10 Duke games at home.
• The 51.5 line has been covered in 14 of the last 20 Duke games.
• The 51.5 line has been covered in the last 2 Duke games at home.

Over 51.5 Probability

The best sportsbooks make it a 51.3% chance that our pick is settled as a winner. However, we think that the probability is close to 60% taking all factors into consideration. This college wager can therefore be backed with confidence.

If you’re wanting bigger odds when wagering on the Totals, then the good news is that you can be in control of the line. Get more juice by betting Over a certain number.

Before placing a wager, see what betting offers are on the table. Our in-depth guide lists the top welcome bonuses right now.

Our Game Prediction

Over 51.5 Points @ -105 Bet Now

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Correct Score Prediction

Tulane 31 - 30 Duke

the Wave are available at massive odds to register a 31-30 victory and they might have the edge. This should be a close matchup and there won’t be much between the teams.

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Tulane vs Duke Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Sportsbooks’ favorites Duke are regarded as likeliest victors for this college game and the -357 about them triumphing means a 78% chance based on their current Moneyline betting odds. Tulane are regarded as a long shot to win and you can currently back them at +280.

The spread is 9.5 and the total points line is currently 51.5. A Total bet relates to the number of points that will be scored overall. If you want to back Over 51.5, it’s -110.

There are a wide range of game lines and team props when it comes to most college football matchups and we recommend visiting the best betting apps to find the wager that matches your view on the game.

Moneyline

Tulane

+280

Duke

-357

Point Spread

Tulane +9.5

-110

Duke -9.5

-110

Total Points

Under 51.5

-110

Over 51.5

-110

As an alternative to the game lines, check out the player prop bets that are available. It’s especially great if you have a view when it comes to First, Last or Anytime Touchdown Scorer, while there are lots of other player and quarterback options.

Micro betting is something that’s really popular with bettors, with college football fans essentially being able to wager in-game when it comes to score, player and team props. Sometimes these are two-way lines where you can bet on the Next Play or Next Drive.

Duke Have Won Six of Their Last Ten Home Games

Duke own a 6-4 mark in their past 10 home games, averaging 29.50 points scored and 28.00 points allowed.

Tulane own a 5-5 mark in their past 10 games on the road, scoring 24.20 points per contest and conceding 29.20.

Last 10 Games		W-L	P	PF	PA	O51.5	U51.5
Duke Home Stats		6-4	57.50	29.50	28.00	6	4
Tulane Away Stats		5-5	53.40	24.20	29.20	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O51.5 = Games Over 51.5 Points
• U51.5 = Games Under 51.5 Points

Latest regular season and playoff games stats.

Tulane Green Wave Stats

Duke Blue Devils Stats

Moneyline

• 8 wins and 2 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 6 wins and 4 defeats in the last 10 home games

Point Spread

• +7.5 Betting Line: Have covered the spread in 8 of the last 10 games
• +7.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• -7.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -7.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 51.70 pts in the previous 10 games
• Game Totals on the Road: An average of 53.40 pts in the previous 10 games on the road
• Over 51.5: Covered in 4 of the previous 10 games
• Over 51.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 28.80 pts and allowed 22.90 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 24.20 pts and allowed 29.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 63.10 pts in the previous 10 games
• Game Totals at Home: An average of 61.50 pts in the previous 10 home games
• Over 51.5: Covered in 6 of the previous 10 games
• Over 51.5 at Home: Covered in 7 of the previous 10 home games
• Team Totals: Have scored an average of 34.80 pts and allowed 28.30 pts in the last 10 games
• Team Totals at Home: Have scored an average of 31.60 pts and allowed 29.90 pts in the last 10 home games

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