USC vs Indiana Prediction, Picks & Odds | 14 Nov 2026
USC vs Indiana Predictions
There’s a generous line of -8.5 when it comes to Indiana in their meeting with USC. The -110 that they cover the spread has plenty of juice and our prediction is it will happen.
Our expert USC vs Indiana picks deliver our Best Bet alongside Player Props, a Same Game Parlay and Correct Score Prediction. Skip directly to the dedicated sections below for a comprehensive look at each play.
USC vs Indiana Preview
USC go up against Indiana at Memorial Stadium, with kickoff scheduled for 15:30 on Saturday, November 14.
USC Trojans won their previous game which was at home. It was a 30-18 triumph at LA Memorial Coliseum against Ohio State Buckeyes.
Indiana Hoosiers won their last game 23-16 (OT), making it successive victories. This was a home win at Memorial Stadium against Minnesota Golden Gophers.
Best Bet
We expect Indiana to cover the -8.5 line on the spread. This is a good number and that’s why we’re playing the favorites at -110 for this college football matchup.
Key stats supporting our main match prediction:
The CFB handicappers at Sportsgambler.com stay on top of injuries and team form that could impact the outcome. We also leave no stone unturned when analyzing the latest stats to support every prediction.
Indiana -8.5 Probability
The best sportsbooks make it a 52.4% chance that our pick is settled as a winner. In our opinion, there’s actually a probability of success closer to 60%. It's therefore regarded as a value wager.
You have the choice to buy or sell points depending on which direction you want to move the line. Decide whether or not you want to play it safer or take a riskier option.
Searching for betting perks? Explore our bonus guide for the freshest sportsbook promo codes, free bets, and offers today.
Player Prop Picks
Jayden Maiava (USC) is priced at -114 to have less than 232.5 passing yards. He may fall short of the QB Passing Yards line, making this prop bet a strong pick.
You can place a bet on King Miller (USC) at -114 to end with fewer than 47.5 rushing yards. There’s a strong case for opting for him to fall short of the required total in the Player Rushing Yards market.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Pick
We’ve compiled a same game parlay that includes Indiana -8.5 on the spread, combined with Under 50.5 and Jayden Maiava (USC) to go Under 232.5 passing yards.
The same game parlay option is fantastic for football bettors wanting a personalised multi-leg wager on the same game. It’s especially good if you have a strong opinion on the likely outcomes and the odds for each selection are combined.
Correct Score Prediction
13
-
30
Indiana
Should you wish to go for a speculative bet, try the Hoosiers to triumph 30-13 on the correct score lines. This should be a fun wager which could potentially yield a huge return.
USC vs Indiana Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Indiana have the shortest price to win this college game, with the sportsbooks giving them a 76% probability due to their -323 Moneyline betting odds. For those wanting to oppose the market leader, you can get +260 about USC.
There is a spread of 8.5 and total points has a line of 50.5. Football bettors regularly enjoy the opportunity to wager on the Totals. Those that want to back Under 50.5 can find odds of -110 available.
If you’re planning to place a college football wager, visit the best betting apps and check out the huge selection of available team props and game lines. Find the odds and betting lines which are the most attractive.
Receiving Yards
Rushing Yards
Indiana Have Taken Nine Wins From Last Ten Home Outings
Indiana have gone 9-1 across their last 10 home games, posting 40.00 points per contest while yielding 11.00.
USC have five wins and five losses in the last 10 games on the road, averaging 26.30 points scored and 26.90 points allowed.
| Last 10 Games | W-L | P | PF | PA | O50.5 | U50.5 | |
|---|---|---|---|---|---|---|---|
 Indiana Home Stats |
9-1 | 51.00 | 40.00 | 11.00 | 6 | 4 | |
 USC Away Stats |
5-5 | 53.20 | 26.30 | 26.90 | 6 | 4 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O50.5 = Games Over 50.5 Points
- U50.5 = Games Under 50.5 Points
Latest regular season and playoff games stats.
USC Stats
Indiana Hoosiers Stats
- 7 wins and 3 defeats in the last 10 games
- 5 wins and 5 defeats in the last 10 games on the road
- +8.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +8.5 Betting Line on the Road: Have covered the spread in 7 of the last 10 games on the road
- -8.5 Betting Line: Have covered the spread in 4 of the last 10 games
- -8.5 Betting Line at Home: Have covered the spread in 6 of the last 10 home games
- Game Totals: An average of 56.70 pts in the previous 10 games
- Game Totals on the Road: An average of 53.20 pts in the previous 10 games on the road
- Over 50.5: Covered in 6 of the previous 10 games
- Over 50.5 on the Road: Covered in 6 of the previous 10 games on the road
- Team Totals: Have scored an average of 31.90 pts and allowed 24.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 26.30 pts and allowed 26.90 pts in the last 10 games on the road
- Game Totals: An average of 45.20 pts in the previous 10 games
- Game Totals at Home: An average of 49.10 pts in the previous 10 home games
- Over 50.5: Covered in 4 of the previous 10 games
- Over 50.5 at Home: Covered in 4 of the previous 10 home games
- Team Totals: Have scored an average of 31.90 pts and allowed 13.30 pts in the last 10 games
- Team Totals at Home: Have scored an average of 36.40 pts and allowed 12.70 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
UCLA
|
9 | 0 | 302 | 127 | 175 | 5-0 | 4-0 | 9W |
|
Indiana
|
8 | 1 | 292 | 112 | 180 | 5-1 | 3-0 | 2W |
Iowa
|
7 | 2 | 250 | 110 | 140 | 4-1 | 3-1 | 2W |
|
USC
|
7 | 2 | 292 | 218 | 74 | 5-1 | 2-1 | 1W |
Illinois
|
6 | 3 | 256 | 207 | 49 | 4-2 | 2-1 | 4W |
Ohio State
|
6 | 3 | 321 | 165 | 156 | 4-1 | 2-2 | 2L |
Oregon
|
6 | 3 | 307 | 199 | 108 | 4-1 | 2-2 | 2W |
Wisconsin
|
6 | 3 | 220 | 147 | 73 | 5-0 | 1-3 | 1W |
Northwestern
|
6 | 3 | 279 | 174 | 105 | 5-1 | 1-2 | 2L |
Minnesota
|
5 | 4 | 222 | 198 | 24 | 4-2 | 1-2 | 2L |
Michigan
|
5 | 4 | 176 | 146 | 30 | 4-3 | 1-1 | 1L |
Nebraska
|
5 | 4 | 272 | 149 | 123 | 4-2 | 1-2 | 4L |
Penn State
|
5 | 4 | 260 | 174 | 86 | 3-2 | 2-2 | 2W |
Washington
|
5 | 4 | 237 | 197 | 40 | 3-3 | 2-1 | 1L |
Purdue
|
3 | 6 | 265 | 291 | -26 | 2-4 | 1-2 | 3L |
Maryland
|
3 | 6 | 249 | 282 | -33 | 1-4 | 2-2 | 1W |
Michigan State
|
3 | 6 | 174 | 212 | -38 | 2-3 | 1-3 | 1W |
Rutgers
|
2 | 7 | 232 | 292 | -60 | 1-4 | 1-3 | 3L |
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