Cleveland Cavaliers
Basketball NBA Tip-off in: days hours minutes seconds
Philadelphia 76ers
  1. Prediction
  2. SGP Picks
  3. Odds
  4. Team Stats
  5. Player Stats
  6. Player Props
  7. Team News
  8. Lineups
  9. Injuries
  10. Rosters
  11. Standings

Cleveland Cavaliers vs Philadelphia 76ers Predictions

Best Bet

Cavaliers +3.5 @ -115

Bet Now BetMGM logo T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Cavs Can Trouble Sixers

We’re confident of the Cavaliers staying close to the Sixers, with our prediction being that they’ll cover the spread. The +3.5 line looks generous at odds of -115.

Our Cavaliers vs Sixers betting guide covers our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Explore the complete analysis behind each pick further down the page.

Cleveland Cavaliers vs Philadelphia 76ers Preview

The Cleveland Cavaliers take the floor against the Philadelphia 76ers in this NBA contest.

Cleveland Cavaliers lost when they last took to the court. At Rocket Arena, they were turned over 130-93 at home to New York Knicks. Donovan Mitchell poured in 31 points, with Evan Mobley contributing 15 and James Harden adding 12.

Philadelphia 76ers got the win in their last game. A 106-100 triumph occurred on the road at Madison Square Garden when meeting New York Knicks. Offensively, Tyrese Maxey led the way, scoring 28, while Jaylen Brown added 19 and LeBron James 14.

H2H: 7 Victories for Cavs in Previous 10 H2H Games

The Cavs beat the Sixers in their last head-to-head matchup. It was a 115-101 scoreline at Rocket Arena. The Cavs have triumphed in their previous four meetings against the Sixers. On the head-to-head front, it has been 7 wins out of 10.

NBA W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
76ers logo 76ers 1 0 1 106 100 6 0-0 1-0 1-0 1-0 1-0 1W
Cavaliers logo Cavaliers 0 0 0 0 0 0 0-0 0-0 0-0 0-0 - -
View Full Standings
Cleveland Cavaliers – Last 10 Games

4 wins and 6 losses in the past 10 games. The Cavs are averaging 105.9 points, 38.3 rebounds, 21.7 assists, 7.7 steals and 5.3 blocks while shooting 44.6% from the field and 73.7% from the free-throw line. The opposition have averaged 111.6 points and 42.5 rebounds per contest.

Donovan Mitchell is averaging 28.3 points and 2.7 (31.4%) 3-pointers made. Evan Mobley averages 7.6 rebounds and James Harden 4.9 assists.

Philadelphia 76ers – Last 10 Games

The Sixers have won 4 and lost 6 of their last 10 contests. Averaging 103.8 points, 38.1 rebounds, 22.4 assists, 5.8 steals and 4.8 blocks per game while shooting 44.7% from the field and 80.7% from the free-throw line. Their opponents have an average of 112.3 points and 46.0 rebounds.

Tyrese Maxey is averaging 23.9 points and 5.3 assists, while Joel Embiid has an average of 6.2 rebounds and Paul George 3.2 (50.0%) 3-pointers made.

Confirmed Starting Lineups

Cleveland Cavaliers lineup: James Harden, Evan Mobley, Peyton Watson, Jarrett Allen, Donovan Mitchell.

Philadelphia 76ers lineup: Tyrese Maxey, Jaylen Brown, Joel Embiid, LeBron James, Valdez Edgecombe.

Best Bet

We’re making Cavaliers against the spread our pick for this NBA contest. The betting line is favorably set at +3.5 and you can secure -115 that this happens.

Key stats supporting our main match prediction:

  • The +3.5 line has been covered by Cavs in 11 of their last 20 games on the road.
  • The -3.5 line hasn’t been covered by Sixers in 4 of their last 5 games.
  • The -3.5 line hasn’t been covered by Sixers in 6 of their last 10 games.
  • The -3.5 line hasn’t been covered by Sixers in 2 consecutive games at home.
  • The -3.5 line hasn’t been covered by Sixers in 8 consecutive games against Cavs.

The handicappers at Sportsgambler.com stay on top of the latest injuries, while recent form also shapes our basketball picks. We combine this insight with up-to-date NBA stats for sharper predictions.

Cavs +3.5 Probability

According to the latest odds, our pick has a 53.5% chance of delivering a return. In the opinion of our cappers, there’s actually a probability of success closer to 60%. This bet can therefore be backed with confidence.

Looking for Bigger Odds?

There's always the option to buy and sell different amounts of points and effectively choose the line which makes the most appeal. It all comes down to how risky or safe you want to play things.

Ready to wager? First, explore top-tier betting promo codes, free bets, and welcome bonuses with our expert bonus guide.

Cavaliers +3.5 @ -115 Bet Now BetMGM logo
BetMGM logo
BetMGM Promo Up To $1500 in Bonus Bets Get Bonus T&C apply. Gamble responsibly 18+
Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Oct 21, 23:02). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.
Published 23:02, 21 October 2026

Player Prop Picks

Top Pick: James Harden Under 7.5 Assists -167 BetMGM logo

James Harden (Cavs) has recorded Under 7.5 assists in 9 of the past 10 games. It therefore stands to reason that he might fall short when it comes to Player Assists and this pick is priced at -167.

Latest James Harden Player Prop Odds


Joel Embiid Under 22.5 Points -115 BetMGM logo

Joel Embiid (76ers) has recorded an average of 17.25 points in the past 4 games. This gives us confidence that he might not cover the line and you can wager on Player Points at betting odds of -115.

Latest Joel Embiid Player Prop Odds

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Same Game Parlay Pick

Spread Cavaliers +3.5
Totals Under 235.5
Player Assists James Harden Under 7.5

We’ve got a same game parlay with three options: Cavs +3.5, Under 235.5 and James Harden (Cavs) to have Under 7.5 assists.

A same game parlay is a great alternative for bettors who want to focus their wagering on a single basketball game. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Cavaliers Cavaliers logo 117 - 115 76ers logo 76ers

We’re expecting this to be a close contest and we’ll take the Cavaliers to win 117-115. This is available at massive odds for those that want to have a speculative wager.

T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Cleveland Cavaliers vs Philadelphia 76ers Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Latest Moneyline Odds Suggest Sixers Victory

With the sportsbooks giving them a 60% probability of winning this NBA game, Philadelphia 76ers might be a popular parlay pick. That is reflected in their -147 Moneyline betting odds. Cleveland Cavaliers are the underdogs at +124 and they’re regarded as least likely to win.

There is a spread of 3.5 and total points has a line of 235.5. A Total wager is always available and can often provide value selections. There’s the chance to back Under 235.5 at -110.

The best betting sites offer hundreds of game lines and team props when it comes to most basketball contests. Make sure you look through all the available options before deciding which bet to place.

Betting Lines & Odds
Donovan Mitchell Favorite to Get Most Points

Donovan Mitchell is favorite when it comes to hitting the most buckets. You can get -103 that he goes Over 26.5 points and -125 when it comes to Under.

Player Points
Donovan Mitchell (Cavaliers)
Over 26.5
-103
Under 26.5
-125
BetMGM Logo
Player Assists
James Harden (Cavaliers)
Over 7.5
+128
Under 7.5
-167
BetMGM Logo
LeBron James (76ers)
Over 7.5
-125
Under 7.5
-103
BetMGM Logo
Tyrese Maxey (76ers)
Over 5.5
-100
Under 5.5
-130
BetMGM Logo
Donovan Mitchell (Cavaliers)
Over 4.5
-137
Under 4.5
+106
BetMGM Logo
Player Rebounds
Evan Mobley (Cavaliers)
Over 8.5
-139
Under 8.5
+107
BetMGM Logo
Joel Embiid (76ers)
Over 7.5
-147
Under 7.5
+113
BetMGM Logo
Jarrett Allen (Cavaliers)
Over 7.5
-145
Under 7.5
+112
BetMGM Logo
LeBron James (76ers)
Over 6.5
-123
Under 6.5
-104
BetMGM Logo
Live market odds and lines updated regularly. All odds subject to change. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Best Betting Offers
Xfinity Mobile Arena
Xfinity Mobile Arena
Sixers Have Collected Five Wins From Last Ten at Home

The Sixers have gone 5-5 across their last 10 home games, averaging 111.00 points scored and 114.00 points allowed.

The Cavs have gone 2-8 across their last 10 road games, posting 104.20 points per contest while yielding 110.40.

In their most recent matchup at Xfinity Mobile Arena, the Cavs got the better of the Sixers 117-115. From the past 10 head-to-heads at Xfinity Mobile Arena, the Sixers have won six while the Cavs have taken four.

Last 10 Games W-L P PF PA O235.5 U235.5
Philadelphia 76ers logo Philadelphia 76ers Home Stats 5-5 225.00 111.00 114.00 2 8
Cleveland Cavaliers logo Cleveland Cavaliers Away Stats 2-8 214.60 104.20 110.40 0 10
  • W-L = Wins-Losses
  • P = Avg. Points
  • PF = Avg. Points For
  • PA = Avg. Points Against
  • O235.5 = Games Over 235.5 Points
  • U235.5 = Games Under 235.5 Points
Last 5 & H2H
Team Stats

Latest regular season and playoff games stats.

Cleveland Cavaliers logo Cleveland Cavaliers Stats
Philadelphia 76ers logo Philadelphia 76ers Stats
Moneyline
  • 4 wins and 6 defeats in the last 10 games
  • 2 wins and 8 defeats in the last 10 games on the road
Moneyline
  • 4 wins and 6 defeats in the last 10 games
  • 5 wins and 5 defeats in the last 10 home games
Point Spread
Point Spread
Total Points
Total Points
Team Stats - Avg/Game
Team Stats - Avg/Game
Team News

Philadelphia 76ers Player Stats & Roster

Player GP MIN TP TA PTS AST 3P REB BLK STL
Tyrese Maxey 1 39.6 28 5 28.0 5.0 2.0 4.0 3.0 3.0
Jaylen Brown 1 34.9 19 6 19.0 6.0 2.0 8.0 1.0 1.0
Valdez Edgecombe 1 34.8 9 1 9.0 1.0 - 4.0 - 1.0

Injuries & Suspensions

Cleveland Cavaliers Injury Table

Type
Name
Info

Philadelphia 76ers Injury Table

Type
Name
Info

Starting Lineups

Philadelphia 76ers logo Philadelphia 76ers Confirmed Lineup
0 Tyrese Maxey
7 Jaylen Brown
21 Joel Embiid
23 LeBron James
77 Valdez Edgecombe
Cleveland Cavaliers logo Cleveland Cavaliers Confirmed Lineup
1 James Harden
4 Evan Mobley
8 Peyton Watson
31 Jarrett Allen
45 Donovan Mitchell

Previous Cleveland Cavaliers Lineups

25 May NBA Playoffs
Knicks 130-93 Cavaliers
23 May NBA Playoffs
Knicks 121-108 Cavaliers
21 May NBA Playoffs
Cavaliers 93-109 Knicks
19 May NBA Playoffs
Cavaliers 104-115 Knicks
17 May NBA Playoffs
Cavaliers 125-94 Pistons
15 May NBA Playoffs
Pistons 115-94 Cavaliers
13 May NBA Playoffs
Cavaliers 117-113 Pistons
11 May NBA Playoffs
Pistons 103-112 Cavaliers
09 May NBA Playoffs
Pistons 109-116 Cavaliers
07 May NBA Playoffs
Cavaliers 97-107 Pistons

Previous Philadelphia 76ers Lineups

20 Oct NBA
76ers 106-100 Knicks
10 May NBA Playoffs
Knicks 144-114 76ers
08 May NBA Playoffs
Knicks 108-94 76ers
06 May NBA Playoffs
76ers 102-108 Knicks
04 May NBA Playoffs
76ers 98-137 Knicks
02 May NBA Playoffs
76ers 109-100 Celtics
30 Apr NBA Playoffs
Celtics 93-106 76ers
28 Apr NBA Playoffs
76ers 113-97 Celtics
26 Apr NBA Playoffs
Celtics 128-96 76ers
24 Apr NBA Playoffs
Celtics 108-100 76ers

NBA Table Select Season

East Atlantic W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
Raptors 1 0 1 135 92 43 1-0 0-0 0-0 1-0 1-0 1W
76ers 1 0 1 106 100 6 0-0 1-0 1-0 1-0 1-0 1W
Knicks 0 1 0 100 106 -6 0-1 0-0 0-1 0-1 0-1 1L
Celtics 0 1 0 113 121 -8 0-0 0-1 0-0 0-1 0-1 1L
Nets 0 1 0 103 110 -7 0-1 0-0 0-0 0-1 0-1 1L
East Central W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
Pistons 1 0 1 121 113 8 1-0 0-0 0-0 1-0 1-0 1W
Pacers 1 0 1 123 120 3 0-0 1-0 0-0 0-0 1-0 1W
Bulls 0 1 0 92 135 -43 0-0 0-1 0-0 0-1 0-1 1L
Cavaliers 0 0 0 0 0 0 0-0 0-0 0-0 0-0 - -
Bucks 0 1 0 116 128 -12 0-0 0-1 0-0 0-1 0-1 1L
East Southeast W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
Hornets 1 0 1 110 103 7 0-0 1-0 0-0 1-0 1-0 1W
Wizards 1 0 1 128 116 12 1-0 0-0 0-0 1-0 1-0 1W
Hawks 1 0 1 132 125 7 0-0 1-0 1-0 1-0 1-0 1W
Heat 0 1 0 106 131 -25 0-1 0-0 0-0 0-0 0-1 1L
Magic 0 1 0 125 132 -7 0-1 0-0 0-1 0-1 0-1 1L
West Northwest W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
Timberwolves 1 0 1 131 106 25 0-0 1-0 0-0 0-0 1-0 1W
Thunder 1 0 1 116 104 12 0-0 1-0 0-0 1-0 1-0 1W
Trail Blazers 1 0 1 124 83 41 1-0 0-0 0-0 1-0 1-0 1W
Nuggets 0 0 0 0 0 0 0-0 0-0 0-0 0-0 - -
Jazz 0 1 0 103 123 -20 0-0 0-1 0-0 0-1 0-1 1L
West Pacific W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
Lakers 1 0 1 127 105 22 1-0 0-0 1-0 1-0 1-0 1W
Clippers 1 0 1 121 96 25 1-0 0-0 1-0 1-0 1-0 1W
Warriors 0 1 0 105 127 -22 0-0 0-1 0-1 0-1 0-1 1L
Suns 0 1 0 83 124 -41 0-0 0-1 0-0 0-1 0-1 1L
Kings 0 1 0 96 121 -25 0-0 0-1 0-1 0-1 0-1 1L
West Southwest W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
Grizzlies 1 0 1 123 103 20 1-0 0-0 0-0 1-0 1-0 1W
Rockets 1 0 1 128 110 18 1-0 0-0 1-0 1-0 1-0 1W
Spurs 0 1 0 104 116 -12 0-1 0-0 0-0 0-1 0-1 1L
Mavericks 0 1 0 110 128 -18 0-0 0-1 0-1 0-1 0-1 1L
Pelicans 0 1 0 120 123 -3 0-1 0-0 0-0 0-0 0-1 1L
Eastern Conference W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
Raptors 1 0 1 135 92 43 1-0 0-0 0-0 1-0 1-0 1W
Wizards 1 0 1 128 116 12 1-0 0-0 0-0 1-0 1-0 1W
Knicks 0 1 0 100 106 -6 0-1 0-0 0-1 0-1 0-1 1L
Pistons 1 0 1 121 113 8 1-0 0-0 0-0 1-0 1-0 1W
Hawks 1 0 1 132 125 7 0-0 1-0 1-0 1-0 1-0 1W
Hornets 1 0 1 110 103 7 0-0 1-0 0-0 1-0 1-0 1W
76ers 1 0 1 106 100 6 0-0 1-0 1-0 1-0 1-0 1W
Pacers 1 0 1 123 120 3 0-0 1-0 0-0 0-0 1-0 1W
Cavaliers 0 0 0 0 0 0 0-0 0-0 0-0 0-0 - -
Nets 0 1 0 103 110 -7 0-1 0-0 0-0 0-1 0-1 1L
Heat 0 1 0 106 131 -25 0-1 0-0 0-0 0-0 0-1 1L
Bucks 0 1 0 116 128 -12 0-0 0-1 0-0 0-1 0-1 1L
Celtics 0 1 0 113 121 -8 0-0 0-1 0-0 0-1 0-1 1L
Magic 0 1 0 125 132 -7 0-1 0-0 0-1 0-1 0-1 1L
Bulls 0 1 0 92 135 -43 0-0 0-1 0-0 0-1 0-1 1L
Western Conference W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
Trail Blazers 1 0 1 124 83 41 1-0 0-0 0-0 1-0 1-0 1W
Spurs 0 1 0 104 116 -12 0-1 0-0 0-0 0-1 0-1 1L
Lakers 1 0 1 127 105 22 1-0 0-0 1-0 1-0 1-0 1W
Warriors 0 1 0 105 127 -22 0-0 0-1 0-1 0-1 0-1 1L
Grizzlies 1 0 1 123 103 20 1-0 0-0 0-0 1-0 1-0 1W
Nuggets 0 0 0 0 0 0 0-0 0-0 0-0 0-0 - -
Rockets 1 0 1 128 110 18 1-0 0-0 1-0 1-0 1-0 1W
Thunder 1 0 1 116 104 12 0-0 1-0 0-0 1-0 1-0 1W
Timberwolves 1 0 1 131 106 25 0-0 1-0 0-0 0-0 1-0 1W
Clippers 1 0 1 121 96 25 1-0 0-0 1-0 1-0 1-0 1W
Mavericks 0 1 0 110 128 -18 0-0 0-1 0-1 0-1 0-1 1L
Pelicans 0 1 0 120 123 -3 0-1 0-0 0-0 0-0 0-1 1L
Suns 0 1 0 83 124 -41 0-0 0-1 0-0 0-1 0-1 1L
Kings 0 1 0 96 121 -25 0-0 0-1 0-1 0-1 0-1 1L
Jazz 0 1 0 103 123 -20 0-0 0-1 0-0 0-1 0-1 1L
NBA W L PCT PPG OPP PPG DIFF Home Road Div Conf Last 10 Strk
Hawks 1 0 1 132 125 7 0-0 1-0 1-0 1-0 1-0 1W
Hornets 1 0 1 110 103 7 0-0 1-0 0-0 1-0 1-0 1W
Pistons 1 0 1 121 113 8 1-0 0-0 0-0 1-0 1-0 1W
Rockets 1 0 1 128 110 18 1-0 0-0 1-0 1-0 1-0 1W
Pacers 1 0 1 123 120 3 0-0 1-0 0-0 0-0 1-0 1W
Clippers 1 0 1 121 96 25 1-0 0-0 1-0 1-0 1-0 1W
Lakers 1 0 1 127 105 22 1-0 0-0 1-0 1-0 1-0 1W
Grizzlies 1 0 1 123 103 20 1-0 0-0 0-0 1-0 1-0 1W
Timberwolves 1 0 1 131 106 25 0-0 1-0 0-0 0-0 1-0 1W
Thunder 1 0 1 116 104 12 0-0 1-0 0-0 1-0 1-0 1W
76ers 1 0 1 106 100 6 0-0 1-0 1-0 1-0 1-0 1W
Trail Blazers 1 0 1 124 83 41 1-0 0-0 0-0 1-0 1-0 1W
Raptors 1 0 1 135 92 43 1-0 0-0 0-0 1-0 1-0 1W
Wizards 1 0 1 128 116 12 1-0 0-0 0-0 1-0 1-0 1W
Celtics 0 1 0 113 121 -8 0-0 0-1 0-0 0-1 0-1 1L
Nets 0 1 0 103 110 -7 0-1 0-0 0-0 0-1 0-1 1L
Bulls 0 1 0 92 135 -43 0-0 0-1 0-0 0-1 0-1 1L
Cavaliers 0 0 0 0 0 0 0-0 0-0 0-0 0-0 - -
Mavericks 0 1 0 110 128 -18 0-0 0-1 0-1 0-1 0-1 1L
Nuggets 0 0 0 0 0 0 0-0 0-0 0-0 0-0 - -
Warriors 0 1 0 105 127 -22 0-0 0-1 0-1 0-1 0-1 1L
Heat 0 1 0 106 131 -25 0-1 0-0 0-0 0-0 0-1 1L
Bucks 0 1 0 116 128 -12 0-0 0-1 0-0 0-1 0-1 1L
Pelicans 0 1 0 120 123 -3 0-1 0-0 0-0 0-0 0-1 1L
Knicks 0 1 0 100 106 -6 0-1 0-0 0-1 0-1 0-1 1L
Magic 0 1 0 125 132 -7 0-1 0-0 0-1 0-1 0-1 1L
Suns 0 1 0 83 124 -41 0-0 0-1 0-0 0-1 0-1 1L
Kings 0 1 0 96 121 -25 0-0 0-1 0-1 0-1 0-1 1L
Spurs 0 1 0 104 116 -12 0-1 0-0 0-0 0-1 0-1 1L
Jazz 0 1 0 103 123 -20 0-0 0-1 0-0 0-1 0-1 1L
  • W = Wins
  • L = Losses
  • PCT = Winning Percentage
  • PPG = Points Per Game
  • OPP PPG = Opponent Points Per Game
  • DIFF = Average Point Differential
  • Home = Home Record
  • Road = Away Record
  • Div = Division Record
  • Conf = Conference Record
  • Last 10 = Record last 10 games
  • Strk = Current Streak

Where to Bet on Basketball Games

Where to Trade Basketball Games

Availability varies by jurisdiction. Some platforms featured may not be accessible in your location. Please check the relevant review page for details.