Oregon vs USC Prediction, Picks & Odds | 21 Feb 2026
College Basketball Betting Preview: Oregon vs USC
The Oregon Ducks go up against the USC Trojans, with tip-off scheduled for 16:00 on Saturday, February 21.
It’s awesome to see USC with a -5.5 line on the spread at odds of -105 as we’re expecting a bigger margin of victory against Oregon.
Oregon Ducks lost their previous game, being beaten at home to Minnesota Golden Gophers 61-44.
USC Trojans were defeated last time out. They were beaten at home to Illinois Fighting Illini by a 101-65 scoreline.
Head-to-Head Statistics
USC won the most recent matchup between these teams. A 82-77 victory was registered against Oregon. Oregon have won six of the previous 10 H2H meetings.
| NCAAB | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
USC
|
18-14 | 2515 | 2494 | 21 | 11-7 | 7-7 | 8L |
Oregon
|
12-20 | 2267 | 2366 | -99 | 10-10 | 2-10 | 1L |
Oregon vs USC Prediction & Picks
We cover the key Oregon vs USC betting angles, showcasing our expert match prediction, correct score selection and a bet builder tailored for the best value.
Game Prediction
USC should be taken against the spread at -5.5 with our pick being for the favorites to achieve a comfortable margin of victory in this college matchup. Back them at the odds of -105 that are available.
The college hoops handicappers at Sportsgambler.com always keep close tabs on team news as it develops. We also rely on recent form and key stats to help shape our basketball picks and guide the final call.
Key Oregon vs USC stats:
USC -5.5 Probability
According to the latest betting odds, our pick has a 51.3% chance of winning. Taking all factors into consideration, our analysts think there’s a stronger chance of success and have a probability interval between 55-60%. This is why we can recommend this college basketball bet.
If you’re hunting for tastier odds, then a Bet Builder could be the perfect way to go. Combine USC to cover the line with other picks until you’re happy with the overall price.
Find top value before betting. Our guide includes the latest free bets and sign-up bonuses from trusted sites.
Same Game Parlay Picks
Take a same game parlay that incorporates USC to cover the -5.5 spread along with Over 144.5. Add in both teams to score 60 points and USC to win on the Result & BTTS lines.
A same game parlay allows bettors to place a multiple wager on the same basketball game. You can go through the available betting lines and select the outcomes that you think will happen. The odds for each pick are then combined together.
Correct Score Prediction
71
-
79
USC
Should you want a bet that can land a monster return, then look no further than the correct score lines. Back the Trojans to win 79-71 and leverage a huge payout if this happens.
Oregon vs USC Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The sportsbooks have USC at -294 when it comes to the Moneyline betting, implying the favorites are 75% likely to win this game according to the latest odds. If you’re looking for an alternative angle, Oregon are trading at +235.
The spread is currently 5.5, with the total points line at 149.5. Basketball bettors love the chance to get an alternative angle by going for a Total wager. If you're keen on Over 149.5, this selection is available at -115.
If you’re planning to place a bet on a college hoops matchup, visit the top basketball betting sites and check out the many available game lines and team props. Find the lines which are the most attractive.
Prop bets don’t involve betting on a team to win and instead might look at a player’s individual performance. For example, the number of Points they might score or the number of Assists they might have.
It’s possible to use stats to your advantage when it comes to college basketball micro betting, especially if you’re predicting outcomes such as the Next Field Goal. Check out the live player, score and team props to see if you can find an angle.
- NCAAB: 03/12 2025 USC 82 Oregon 77
- NCAAB: 01/03 2025 USC 61 Oregon 82
- NCAAB: 05/12 2024 Oregon 68 USC 60
- NCAAB: 02/02 2024 Oregon 78 USC 69
- NCAAB: 29/12 2023 USC 74 Oregon 82
- NCAAB: 10/02 2023 USC 60 Oregon 78
- NCAAB: 27/02 2022 USC 70 Oregon 69
- NCAAB: 16/01 2022 Oregon 79 USC 69
- NCAAB: 29/03 2021 Oregon 68 USC 82
- NCAAB: 23/02 2021 Oregon 58 USC 72
Latest regular season and playoff games stats.
Oregon Stats
USC Stats
- 1 win and 9 defeats in the last 10 games
- 1 win and 9 defeats in the last 10 games on the road
- +5.5 Betting Line: Have covered the spread in 2 of the last 10 games
- +5.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road
- -5.5 Betting Line: Have covered the spread in 2 of the last 10 games
- -5.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
- Game Totals: An average of 138.40 pts in the previous 10 games
- Game Totals on the Road: An average of 148.50 pts in the previous 10 games on the road
- Over 144.5: Covered in 5 of the previous 10 games
- Over 144.5 on the Road: Covered in 5 of the previous 10 games on the road
- Team Totals: Have scored an average of 62.30 pts and allowed 76.10 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 69.30 pts and allowed 79.20 pts in the last 10 games on the road
- Game Totals: An average of 152.10 pts in the previous 10 games
- Game Totals at Home: An average of 153.00 pts in the previous 10 home games
- Over 144.5: Covered in 7 of the previous 10 games
- Over 144.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 74.80 pts and allowed 77.30 pts in the last 10 games
- Team Totals at Home: Have scored an average of 78.70 pts and allowed 74.30 pts in the last 10 home games
NCAAB Table Select Season
| Big Ten | Overall | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|
Michigan
|
31-3 | 2952 | 2353 | 599 | 19-2 | 12-1 | 1L |
Nebraska
|
26-6 | 2473 | 2119 | 354 | 19-3 | 7-3 | 1L |
Michigan State
|
25-7 | 2526 | 2189 | 337 | 17-3 | 8-4 | 2L |
Purdue
|
27-8 | 2858 | 2455 | 403 | 16-5 | 11-3 | 4W |
Illinois
|
24-8 | 2700 | 2234 | 466 | 15-6 | 9-2 | 1L |
Wisconsin
|
24-10 | 2822 | 2581 | 241 | 16-2 | 8-8 | 1L |
UCLA
|
23-11 | 2643 | 2414 | 229 | 18-3 | 5-8 | 1L |
Ohio State
|
21-12 | 2633 | 2402 | 231 | 15-5 | 6-7 | 1L |
Iowa
|
21-12 | 2482 | 2177 | 305 | 17-3 | 4-9 | 1L |
Indiana
|
18-14 | 2501 | 2309 | 192 | 15-6 | 3-8 | 2L |
|
USC
|
18-14 | 2515 | 2494 | 21 | 11-7 | 7-7 | 8L |
Washington
|
16-17 | 2545 | 2430 | 115 | 11-6 | 5-11 | 1L |
Minnesota
|
15-17 | 2241 | 2193 | 48 | 13-8 | 2-9 | 1L |
Northwestern
|
15-19 | 2487 | 2447 | 40 | 11-9 | 4-10 | 1L |
Rutgers
|
14-19 | 2329 | 2479 | -150 | 11-7 | 3-12 | 1L |
|
Oregon
|
12-20 | 2267 | 2366 | -99 | 10-10 | 2-10 | 1L |
Penn State
|
12-20 | 2358 | 2539 | -181 | 10-10 | 2-10 | 3L |
Maryland
|
12-21 | 2300 | 2527 | -227 | 9-8 | 3-13 | 1L |
- Overall = Overall Wins-Losses
- PF = Total Points For
- PA = Total Points Against
- N. Pts = Point Differential
- Home = Home Record
- Away = Away Record
- Strk = Current Streak
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