Cruz Azul vs Santos Laguna Prediction, Betting Tips, Lineups & Odds | 06 Sep 2026
Cruz Azul vs Santos Laguna Predictions
We can bank some insurance on the outsiders by wagering Santos Laguna +1.25 at -106 on the Asian Handicap. Our money is divided between +1 and +1.5 and we’re happy to back them against Cruz Azul.
Explore our full Cruz Azul vs Santos Laguna betting preview, which features the complete write-up for our main match prediction, alongside our correct score prediction, player prop picks, corners prediction and bet builder tips.
Cruz Azul vs Santos Laguna Preview
Cruz Azul go head-to-head with Santos Laguna at Estadio Banorte, with kick-off set for 19:00 on Sunday 6 September.
Cruz Azul have been handed two Liga MX home losses in a row. In their last league game, they beat Club Necaxa away by a 3-1 scoreline at Estadio Victoria. Joel Huiqui's team enjoyed 54% possession and had eight shots on target, while Jeremy Marquez, Nicolas Ibanez and Willer Ditta scored one goal each.
Santos Laguna drew 0-0 against Tigres UANL in their previous game. This was on home soil at Estadio Nuevo Corona. The Comarca Lagunera outfit had the lion’s share of the ball boasting 59% possession and three shots on goal.
H2H: 2-1 Win for Cruz Azul in Last H2H Battle
Cruz Azul have beaten Santos on four consecutive occasions. Their last clash saw Cruz Azul enjoy a 2-1 away win at Estadio Nuevo Corona. The previous 10 H2H meetings have involved five Cruz Azul wins, three Santos victories and two draws.
| Liga MX | G | W | D | L | GF | GA | GD | GD | P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 6 |  Cruz Azul |
12 | 6 | 2 | 4 | 27 | 21 | 6 | 27:21 | 20 |
| 9 |  Santos Laguna |
12 | 5 | 1 | 6 | 17 | 16 | 1 | 17:16 | 16 |
Cruz Azul have 5 wins, 3 losses and 2 draws, averaging 1.7 goals from 6.0 shots on goal and 12.7 attempts. La Máquina Celeste have averaged 47.6% possession and 6.0 corners per game, with the opposition getting 1.5 goals from 3.7 shots on goal, 8.3 attempts and 4.3 corners.
Top scorer Jeremy Marquez has found the net 4 times, Nicolas Ibanez 3, with Agustin Palavecino and Christian Ebere both scoring 2. Leading assistor is Carlos Rodriguez with 5.
Santos have won 1, lost 8 and drawn 1, averaging 8.3 attempts, 2.5 shots on goal and 0.9 goals. Renato Paiva's side average 50.4% possession, 5.9 corners in their favour and 5.1 corners against, while 1.8 goals have been conceded from 5.8 shots on goal and 12.6 attempts.
Lucas Di Yorio has scored 3 goals, followed by Ezequiel Bullaude, Eduardo Aguirre, Emmanuel Echeverria and Aldo Lopez on 1. Ezequiel Bullaude has managed to clock up 3 assists in the last 10 games.
Confirmed Lineups
Cruz Azul confirmed lineup (5-3-2): Kevin Mier (GK), Willer Ditta, Amaury Garcia, Jesus Orozco, Jeremy Marquez, Omar Campos, Agustin Palavecino, Rogelio Gonzalez, Carlos Rodriguez, Nicolas Ibanez, Luka Romero.
Santos Laguna confirmed lineup (4-2-3-1): Carlos Acevedo (GK), Mauricio Cuevas, Jonathan Perez Sanchez, Felipe Sanchez, Efrain Orona, Salvador Mariscal, Aldo Lopez, Diego Gonzalez, Luis Gomez, Kevin Palacios, Ezequiel Bullaude.
Main Match Prediction
We can’t pass up the chance to wager Santos Laguna +1.25 on the Asian Handicap. Take the price of -106 for this Liga MX match in the expectation that the underdogs can run their opponents close.
Key stats supporting our main match prediction (league matches):
Getting the lowdown on injuries and studying the Liga MX form guide are important duties ahead of making football predictions. We also place great emphasis on the stats and a data-led approach can sometimes be effective.
The betting odds at the top bookies suggest our pick carries a 51.5% chance of winning. Based on our experts research, we calculate the actual probability to be closer to 60%. That means we’re regarding it as a value bet.
If you are looking for larger odds, there’s plenty of choice when it comes to selling goals. Taking this option involves more risk and a bigger potential return.
Don’t start wagering without checking our guide to the newest betting promo codes, best welcome bonuses and free bet offers.
Correct Score Prediction
2
-
2
Santos
There are attractive odds of +950 when it comes to a 2-2 draw being played out. This is a risky but potentially more rewarding bet, with this correct score option providing appeal.
Player Prop Picks
Fran Villalba (Santos) can be wagered to register at least one shot on goal at +145. We’ll take a chance with this Shots on Target pick as the betting odds look pretty attractive.
Ezequiel Bullaude (Santos) has registered three goals in his past nine Liga MX matches away from home. We think there’s value in backing him for an Anytime Goalscorer prop bet at +370 which will hopefully see him find the net.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Corners Prediction
The 3.5 corners line has been covered by Santos in six consecutive matches, with Cruz Azul conceding over 3.5 corners in their past four games. There’s an opportunity to go over the Santos Team Corners line and we’re expecting this to happen, with odds of -102 available.
Cruz Azul
Santos
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Bet Builder Tips
We’ve lined up a same-game multi including these picks: Santos to cover the +1.25 Asian Handicap, Yes on the BTTS market merged with Fran Villalba (Santos) to have a minimum of one shot on target.
A football bet builder is a fantastic way of cheering on different selections within the same game. It’s a great bet to have if you’re confident of certain outcomes, especially as the price for each selection is combined.
Cruz Azul vs Santos Laguna Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The bookmakers take few chances with their latest odds of -303 for Cruz Azul winning which suggests that they have a 75% chance in this Liga MX encounter. If you want to wager on the underdog, Santos Laguna have been priced up at +650.
You can take advantage of the Half-Time Result market if you think a team will lead at the break. There's the chance to back Cruz Azul at -149, go for Santos at +480 or take the draw at +170.
There’s a high probability that Over 2.5 Goals will be netted according to the current prices. For those expecting both sides to find the net, Both Teams to Score Yes is available at -172.
The best football betting sites have excellent coverage for the latest Liga MX games. They supply customers with hundreds of markets and it’s down to you to find the best angle.
Those interested in favourite Gabriel Matías Fernández to find the net first are able to get +310. If the Anytime Goalscorer angle makes more appeal, then this is -114.
Stats: Last 10 Liga MX matches only.
Cruz Azul have clocked up four wins, three draws and three defeats in the past 10 home games, recording an average of 1.60 goals per match and conceding 1.20.
The past six Santos Laguna games on the road have ended in defeat. The Comarca Lagunera outfit have finished with eight defeats, one win and one draw in the past 10 away matches, netting an average of 1.20 goals per game and conceding 2.80.
Cruz Azul won 3-2 when they last played Santos at Estadio Banorte. It’s been four Cruz Azul wins, two draws and two Santos victories in the past 8 H2H meetings at Estadio Banorte.
| Last 10 League Games | W-D-L | G | GF | GA | O2.5 | U2.5 | B-Y | B-No | |
|---|---|---|---|---|---|---|---|---|---|
| Cruz Azul Home Stats |
4-3-3 | 2.80 | 1.60 | 1.20 | 6 | 4 | 6 | 4 | |
| Santos Laguna Away Stats |
1-1-8 | 4.00 | 1.20 | 2.80 | 9 | 1 | 7 | 3 | |
- W-D-L = Wins-Draws-Losses
- G = Avg. Goals
- GF = Avg. Goals For
- GA = Avg. Goals Against
- O2.5 = Matches Over 2.5 Goals
- U2.5 = Matches Under 2.5 Goals
- B-Y = Matches BTTS Yes
- B-No = Matches BTTS No
- Liga MX: 04/03 2026 Santos 1 Cruz Azul 2
- Liga MX: 17/08 2025 Cruz Azul 3 Santos 2
- Liga MX: 20/02 2025 Santos 0 Cruz Azul 1
- Liga MX: 03/11 2024 Cruz Azul 2 Santos 0
- Liga MX: 10/03 2024 Santos 3 Cruz Azul 0
- Liga MX: 21/08 2023 Cruz Azul 2 Santos 2
- Liga MX: 30/04 2023 Cruz Azul 3 Santos 2
- Liga MX: 07/08 2022 Santos 4 Cruz Azul 0
- Liga MX: 28/02 2022 Cruz Azul 1 Santos 2
- Liga MX: 02/08 2021 Santos 1 Cruz Azul 1
Cruz Azul League Stats
Santos Laguna League Stats
- 5 wins, 3 defeats and 2 draws in the previous 10 matches
- 4 wins, 3 defeats and 3 draws in the previous 10 home matches
- 1 win, 8 defeats and 1 draw in the previous 10 matches
- 1 win, 8 defeats and 1 draw in the previous 10 away matches
- An average of 1.70 goals scored and 1.50 conceded in the previous 10 matches
- An average of 1.60 goals scored and 1.20 conceded in the previous 10 home matches
- An average of 3.20 goals per game in the previous 10 matches
- An average of 2.80 goals per game in the previous 10 home matches
- BTTS Yes in 8 of the previous 10 matches
- BTTS Yes in 6 of the previous 10 home matches
- Over 2.5 Goals in 8 of the previous 10 matches
- Over 2.5 Goals in 6 of the previous 10 home matches
- An average of 0.90 goals scored and 1.80 conceded in the previous 10 matches
- An average of 1.20 goals scored and 2.80 conceded in the previous 10 away matches
- An average of 2.70 goals per game in the previous 10 matches
- An average of 4.00 goals per game in the previous 10 away matches
- BTTS Yes in 3 of the previous 10 matches
- BTTS Yes in 7 of the previous 10 away matches
- Over 2.5 Goals in 5 of the previous 10 matches
- Over 2.5 Goals in 9 of the previous 10 away matches
- An average of 6.00 corners awarded and 4.30 corners conceded in the last 10 matches
- An average of 6.10 corners awarded and 2.80 corners against in the last 10 home matches
- An average of 10.30 corners awarded in the last 10 matches
- An average of 8.90 corners awarded in the last 10 home matches
- Had the most corners in 5 and least corners in 2 of the last 10 matches
- Had the most corners in 7 and least corners in 1 of the last 10 home matches
- An average of 5.90 corners awarded and 5.10 corners conceded in the last 10 matches
- An average of 5.10 corners awarded and 4.60 corners against in the last 10 away matches
- An average of 11.00 corners awarded in the last 10 matches
- An average of 9.70 corners awarded in the last 10 away matches
- Had the most corners in 4 and least corners in 5 of the last 10 matches
- Had the most corners in 4 and least corners in 4 of the last 10 away matches
- An average of 47.60% possession in the last 10 matches
- An average of 48.80% possession in the last 10 home matches
- Most possession in 7 of the last 10 matches
- Most possession in 6 of the last 10 home matches
- An average of 50.40% possession in the last 10 matches
- An average of 47.70% possession in the last 10 away matches
- Most possession in 6 of the last 10 matches
- Most possession in 4 of the last 10 away matches
- Top Scorers for Cruz Azul this season are Jeremy Marquez (3), Nicolas Ibanez (3), Agustin Palavecino (1)
- Top Assistors for Cruz Azul this season are Carlos Rodriguez (4), Jose Paradela (2), Luka Romero (2)
Cruz Azul vs Santos Laguna Lineups & Team News
Don’t miss the latest Cruz Azul vs Santos team news before you bet. We’ll share both predicted and confirmed lineups for the Liga MX along with the latest injury news.
Cruz Azul Confirmed Lineup 5-3-2
Santos Laguna Confirmed Lineup 4-2-3-1
Cruz Azul Confirmed Lineup 5-3-2
Santos Laguna Confirmed Lineup 4-2-3-1
Cruz Azul Substitutes
- 1Andres Gudino
- 2Alan Mozo
- 6Erik Lira
- 10Andres Montano
- 11Christian Ebere
- 12Alan Montes
- 20Jose Paradela
- 21Gabriel Fernandez
- 22Jorge Rodarte
- 33Gonzalo Piovi
Santos Laguna Substitutes
- 4Jose Abella
- 6Javier Guemez
- 17Emmanuel Echeverria
- 18Franco Pardo
- 19Eduardo Aguirre
- 20Esteban Lozano
- 21Fran Villalba
- 24Diego Medina
- 26Ramiro Sordo
- 33Hector Holguin
Previous Cruz Azul Lineups
Previous Santos Laguna Lineups
Injuries & Suspensions
Cruz Azul Player Stats & Squad
Manager: Joel Huiqui
Santos Laguna Player Stats & Squad
Liga MX Table| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | América | 11 | 7 | 3 | 1 | 27:14 | 24 |
| 2 | Guadalajara | 13 | 6 | 5 | 2 | 20:12 | 23 |
| 3 | Toluca | 12 | 6 | 3 | 3 | 26:16 | 21 |
| 4 | León | 13 | 6 | 3 | 4 | 20:17 | 21 |
| 5 | Atlas | 12 | 6 | 3 | 3 | 19:18 | 21 |
| 6 | Cruz Azul | 12 | 6 | 2 | 4 | 27:21 | 20 |
| 7 | Querétaro | 12 | 6 | 2 | 4 | 16:15 | 20 |
| 8 | Monterrey | 11 | 5 | 2 | 4 | 19:16 | 17 |
| 9 | Santos Laguna | 12 | 5 | 1 | 6 | 17:16 | 16 |
| 10 | Tijuana | 11 | 4 | 4 | 3 | 15:14 | 16 |
| 11 | Pumas | 12 | 4 | 4 | 4 | 19:20 | 16 |
| 12 | Puebla | 12 | 4 | 4 | 4 | 12:13 | 16 |
| 13 | San Luis | 13 | 4 | 4 | 5 | 18:22 | 16 |
| 14 | Tigres | 13 | 3 | 5 | 5 | 14:18 | 14 |
| 15 | Atlante | 13 | 3 | 5 | 5 | 14:19 | 14 |
| 16 | Pachuca | 12 | 3 | 4 | 5 | 19:16 | 13 |
| 17 | Necaxa | 13 | 2 | 3 | 8 | 15:26 | 9 |
| 18 | Juárez | 13 | 1 | 1 | 11 | 8:32 | 4 |
| # | Team | G | W | D | L | +/- | P |
|---|---|---|---|---|---|---|---|
| 1 | Monterrey | 6 | 4 | 1 | 1 | 13:7 | 13 |
| 2 | Cruz Azul | 7 | 4 | 1 | 2 | 17:12 | 13 |
| 3 | Guadalajara | 7 | 4 | 1 | 2 | 11:7 | 13 |
| 4 | Tijuana | 7 | 4 | 1 | 2 | 10:6 | 13 |
| 5 | León | 6 | 4 | 0 | 2 | 12:9 | 12 |
| 6 | América | 5 | 3 | 2 | 0 | 11:3 | 11 |
| 7 | Tigres | 6 | 3 | 2 | 1 | 9:7 | 11 |
| 8 | Toluca | 6 | 3 | 1 | 2 | 16:9 | 10 |
| 9 | Santos Laguna | 6 | 3 | 1 | 2 | 8:3 | 10 |
| 10 | San Luis | 7 | 2 | 2 | 3 | 9:11 | 8 |
| 11 | Querétaro | 5 | 2 | 1 | 2 | 7:6 | 7 |
| 12 | Puebla | 5 | 1 | 3 | 1 | 6:6 | 6 |
| 13 | Pumas | 6 | 1 | 3 | 2 | 9:11 | 6 |
| 14 | Atlante | 6 | 1 | 3 | 2 | 7:9 | 6 |
| 15 | Atlas | 6 | 1 | 3 | 2 | 6:9 | 6 |
| 16 | Necaxa | 7 | 2 | 0 | 5 | 8:14 | 6 |
| 17 | Juárez | 7 | 1 | 1 | 5 | 5:12 | 4 |
| 18 | Pachuca | 5 | 0 | 3 | 2 | 9:11 | 3 |
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