Colorado vs Northwestern Prediction, Picks & Odds | 19 Sep 2026
College Football Betting Preview: Colorado vs Northwestern
Colorado face Northwestern at Ryan Field, with kickoff scheduled for 19:30 on Saturday, September 19.
There’s a generous line of -3.5 when it comes to Northwestern in their meeting with Colorado. The -110 that they cover the spread has plenty of juice and our prediction is it will happen.
Colorado Buffaloes made it back-to-back wins after a 52-21 home success over Weber State Wildcats at Folsom Field.
Northwestern Wildcats won their last game which was at home. It was a 34-18 triumph at Northwestern Medicine Field at Martin Stadium against South Dakota State.
Quarterbacks
Julian Lewis
Aidan Chiles
Colorado vs Northwestern Prediction & Picks
Our Colorado vs Northwestern betting outlook has it all, including a trusted match forecast, our predicted score, top player prop picks and a hand-picked bet builder.
Game Prediction
It’s time to go for Northwestern against the spread, especially with an attractive -3.5 line at -110. Our pick is that the favorites can achieve a comfortable win in this college football battle.
The CFB handicappers at Sportsgambler.com stay on top of injuries and team form that could impact the outcome. We also leave no stone unturned when analyzing the latest stats to support every prediction.
Key Colorado vs Northwestern stats:
Northwestern -3.5 Probability
According to the top sportsbooks, our pick has a 52.4% chance of delivering a return. However, we have this figure at close to 60% based on our in-depth research. This is why we can recommend this college wager.
If you’re hunting for tastier odds, then a Bet Builder could be the way to go. Combine Northwestern against the spread with other picks until you’re happy with the overall price.
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Player Prop Picks
Aidan Chiles (Northwestern) can be backed at -114 to reach over 225.5 passing yards. We feel confident that he’ll cover the QB Passing Yards line, which looks generous.
Micah Welch (Colorado) is available at -114 to exceed 41.5 rushing yards. He looks capable of covering the line and that leads us to taking this Player Rushing Yards bet.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Take a same game parlay that incorporates Northwestern to cover the -3.5 spread along with Over 48.5 points. We’ve also gone for Aidan Chiles (Northwestern) to go Over 225.5 passing yards.
The same game parlay option allows you to combine different outcomes within the same game. You need all your predictions to be correct although bettors love to place a tailored football bet on the event which interests them most.
Correct Score Prediction
23
-
31
Northwestern
There’s a massive payout on the cards should you correctly predict the correct score. We’re siding with the Wildcats to enjoy a 31-23 victory which will hopefully go close.
Colorado vs Northwestern Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The sportsbooks’ betting odds have Northwestern as -175 favorites for this college game, implying that they are 64% likely to win. For those wanting to oppose the market leader, you can get +146 about Colorado.
The current spread is 3.5 and the total points line is 48.5. A Total bet relates to the number of points that will be scored overall. If you’re going for Under 48.5, this outcome can be backed at -115.
There are a wide range of game lines and team props when it comes to most college football matchups and we recommend visiting the best betting apps to find the wager that matches your view on the game.
Receiving Yards
Rushing Yards
Passing Yards
Latest regular season and playoff games stats.
Colorado Buffaloes Stats
Northwestern Wildcats Stats
- 3 wins and 7 defeats in the last 10 games
- 4 wins and 6 defeats in the last 10 games on the road
- +3.5 Betting Line: Have covered the spread in 4 of the last 10 games
- +3.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road
- -3.5 Betting Line: Have covered the spread in 4 of the last 10 games
- -3.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
- Game Totals: An average of 51.90 pts in the previous 10 games
- Game Totals on the Road: An average of 52.40 pts in the previous 10 games on the road
- Over 48.5: Covered in 6 of the previous 10 games
- Over 48.5 on the Road: Covered in 7 of the previous 10 games on the road
- Team Totals: Have scored an average of 20.90 pts and allowed 31.00 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 24.20 pts and allowed 28.20 pts in the last 10 games on the road
- Game Totals: An average of 46.00 pts in the previous 10 games
- Game Totals at Home: An average of 47.40 pts in the previous 10 home games
- Over 48.5: Covered in 5 of the previous 10 games
- Over 48.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 26.20 pts and allowed 19.80 pts in the last 10 games
- Team Totals at Home: Have scored an average of 29.00 pts and allowed 18.40 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Indiana
|
2 | 0 | 107 | 16 | 91 | 2-0 | 0-0 | 2W |
Washington
|
2 | 0 | 40 | 24 | 16 | 2-0 | 0-0 | 2W |
Wisconsin
|
1 | 1 | 49 | 50 | -1 | 1-0 | 0-1 | 1W |
Purdue
|
1 | 1 | 80 | 57 | 23 | 1-1 | 0-0 | 1L |
Oregon
|
1 | 1 | 65 | 66 | -1 | 1-0 | 0-1 | 1L |
Ohio State
|
1 | 1 | 79 | 27 | 52 | 1-0 | 0-1 | 1L |
Minnesota
|
1 | 1 | 72 | 45 | 27 | 1-1 | 0-0 | 1L |
Illinois
|
1 | 1 | 69 | 54 | 15 | 1-1 | 0-0 | 1L |
USC
|
3 | 0 | 130 | 56 | 74 | 3-0 | 0-0 | 3W |
Iowa
|
2 | 0 | 56 | 13 | 43 | 2-0 | 0-0 | 2W |
UCLA
|
2 | 0 | 73 | 34 | 39 | 1-0 | 1-0 | 2W |
Penn State
|
2 | 0 | 72 | 9 | 63 | 1-0 | 1-0 | 2W |
|
Northwestern
|
1 | 0 | 34 | 18 | 16 | 1-0 | 0-0 | 1W |
Nebraska
|
2 | 0 | 105 | 28 | 77 | 2-0 | 0-0 | 2W |
Michigan
|
2 | 0 | 30 | 22 | 8 | 2-0 | 0-0 | 2W |
Michigan State
|
2 | 0 | 65 | 27 | 38 | 2-0 | 0-0 | 2W |
Maryland
|
2 | 0 | 100 | 14 | 86 | 1-0 | 1-0 | 2W |
Rutgers
|
0 | 2 | 42 | 65 | -23 | 0-1 | 0-1 | 2L |
| Big 12 | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
BYU
|
2 | 0 | 91 | 24 | 67 | 2-0 | 0-0 | 2W |
Cincinnati
|
2 | 0 | 96 | 25 | 71 | 2-0 | 0-0 | 2W |
|
Colorado
|
2 | 0 | 66 | 34 | 32 | 1-0 | 1-0 | 2W |
Houston
|
2 | 0 | 110 | 26 | 84 | 2-0 | 0-0 | 2W |
Kansas State
|
2 | 0 | 105 | 10 | 95 | 2-0 | 0-0 | 2W |
Texas Tech
|
2 | 0 | 68 | 34 | 34 | 1-0 | 1-0 | 2W |
Utah
|
2 | 0 | 109 | 24 | 85 | 2-0 | 0-0 | 2W |
West Virginia
|
2 | 0 | 83 | 31 | 52 | 2-0 | 0-0 | 2W |
Baylor
|
1 | 1 | 60 | 20 | 40 | 1-0 | 0-1 | 1W |
Iowa State
|
1 | 1 | 51 | 26 | 25 | 1-0 | 0-1 | 1L |
Kansas
|
1 | 1 | 72 | 44 | 28 | 1-1 | 0-0 | 1L |
Oklahoma State
|
1 | 1 | 49 | 55 | -6 | 1-0 | 0-1 | 1W |
TCU
|
1 | 1 | 73 | 22 | 51 | 1-1 | 0-0 | 1W |
UCF
|
1 | 1 | 80 | 18 | 62 | 1-0 | 0-1 | 1L |
Arizona
|
1 | 1 | 52 | 35 | 17 | 1-0 | 0-1 | 1L |
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