North Carolina Tar Heels (UNC)
American Football NCAAF Memorial Stadium Sat 19 Sep 12:00
Clemson Tigers
  1. Prediction
  2. SGP Picks
  3. Odds
  4. Player Props
  5. Stats
  6. Standings

College Football Betting Preview: North Carolina vs Clemson

North Carolina face Clemson at Memorial Stadium, with kickoff scheduled for 12:00 on Saturday, September 19.

Our Best Pick is Clemson Against the Spread

We are confident that Clemson will cover the spread. -3.5 seems a more than generous line and you can get -102 that they will win by a bigger margin when playing North Carolina.

Clemson 38-10 Win in Previous H2H Encounter

North Carolina Tar Heels beat East Tennessee State Buccaneers in their previous game, making it back-to-back victories. It was a 35-3 home win at Kenan Stadium.

Clemson Tigers last game saw them claim a 22-7 home win over Georgia Southern Eagles at Memorial Stadium.

Head-to-Head Statistics

The scoreline was 38-10 in favor of Clemson when they last played North Carolina, with the matchup taking place at Kenan Stadium. For the past 4 games involving these teams, there has been a Clemson win every time.

Quarterbacks

North Carolina vs Clemson Prediction & Picks

We’ve broken down North Carolina vs Clemson from every angle, offering our expert match prediction, expected final score, best player prop recommendations and a well-constructed bet builder.

Game Prediction

Don’t miss the opportunity to side with Clemson on the spread at -3.5. On the face of it, this seems a generous line and odds of -102 can be backed for this college football matchup.

Team news plays a key role in our college football forecasts and we’re always tracking players with injury concerns. We also stay on top of the form guide, supported by detailed stats that help paint a clearer picture of what to expect

Key North Carolina vs Clemson stats:

  • The -3.5 line has been covered by Clemson in 13 of their last 20 games at home.
  • The -3.5 line has been covered by Clemson in 3 of their last 5 games.
  • The +3.5 line hasn’t been covered by North Carolina in 3 of their last 5 games.
  • The -3.5 line has been covered by Clemson in 3 consecutive games against North Carolina.

Clemson -3.5 Probability

If you go by the best sportsbooks, our pick has a 50.5% prospect of winning. However, our cappers think that the probability is close to 60% taking all factors into consideration. The wager can be recommended for this precise reason.

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Our Game Prediction
Clemson -3.5 @ -102 Bet Now BetMGM logo
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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Sep 17, 18:25). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.
Published 18:25, 17 September 2026

Player Prop Picks

Top Pick: Tait Reynolds Over 179.5 Passing Yards -114 BetMGM logo

Tait Reynolds (Clemson) is priced at -114 to surpass 179.5 passing yards. There’s an opportunity to place a QB Passing Yards bet, with him capable of covering an appealing line.

Latest Tait Reynolds Player Prop Odds

T.J. Moore Over 54.5 Receiving Yards -114 BetMGM logo

The odds for T.J. Moore (Clemson) to reach over 54.5 receiving yards are -114. With confidence, we can back him to cover the generous Player Receiving Yards line, as all the signs point to him reaching the expected total.

Latest T.J. Moore Player Prop Odds

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Same Game Parlay Picks

Spread Clemson -3.5
Totals Under 43.5
Passing Yards Tait Reynolds Over 179.5

Try out our same game parlay pick which starts with Clemson -3.5. We’ve also gone for Under 43.5 points and Tait Reynolds (Clemson) to have Over 179.5 passing yards.

There are many options when you place a same game parlay. You can go through the football lines and identify your favorite outcomes before combining the odds on the bet slip. Personalised betting doesn’t come any better.

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

North Carolina North Carolina logo 13 - 23 Clemson logo Clemson

There are some huge returns lying in wait if you can get the correct score right. With this in mind, we’ll have a play on Clemson to enjoy a 23-13 winning scoreline.

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North Carolina vs Clemson Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Clemson Trading at Shorter Odds Than UNC

The sportsbooks’ betting odds have Clemson as -161 favorites for this college game, implying that they are 62% likely to win. North Carolina are trading at bigger odds than their opponents and they can be backed at +134.

3.5 is the spread and 43.5 is the total points line. The beauty of the Totals is that you only have to choose from one of two options. If you want to bet Under 43.5, there are odds of -105.

There’s no shortage of betting opportunities when it comes to college football. The best betting apps offer a wide variety of team props and game lines for each game, so be sure to explore both the pre-game and in-game markets before making your pick.

Player Odds

Receiving Yards

Rushing Yards

Passing Yards

Billy Edwards Jr. (UNC)
Over 203.5
-114
Under 203.5
-114
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Tait Reynolds (Clemson)
Over 179.5
-114
Under 179.5
-114
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Live market odds and lines updated regularly. All odds subject to change. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
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Memorial Stadium
Memorial Stadium

Clemson Rolling at Home

Clemson have chalked up three straight victories at Memorial Stadium. They have gone 5-5 across their last 10 home games, scoring 28.30 points per contest and conceding 20.60.

North Carolina have gone 5-5 across their last 10 road games, putting up 21.70 points on average and giving up 21.40.

The last time these teams met at Memorial Stadium, Clemson came out on top 31-20 against North Carolina.

Last 10 Games W-L P PF PA O43.5 U43.5
Clemson logo Clemson Home Stats 5-5 48.90 28.30 20.60 5 5
North Carolina logo North Carolina Away Stats 5-5 43.10 21.70 21.40 4 6
  • W-L = Wins-Losses
  • P = Avg. Points
  • PF = Avg. Points For
  • PA = Avg. Points Against
  • O43.5 = Games Over 43.5 Points
  • U43.5 = Games Under 43.5 Points
Last 5 & H2H
Team Stats

Latest regular season and playoff games stats.

North Carolina Tar Heels logo North Carolina Tar Heels Stats
Clemson Tigers logo Clemson Tigers Stats
Moneyline
  • 4 wins and 6 defeats in the last 10 games
  • 5 wins and 5 defeats in the last 10 games on the road
Moneyline
  • 6 wins and 4 defeats in the last 10 games
  • 4 wins and 6 defeats in the last 10 home games
Point Spread
Point Spread
Total Points
Total Points
NCAAF Standings Select Season
Atlantic Coast W L PF PA N. Pts Home Away Strk
Miami 2 0 122 13 109 1-0 1-0 2W
SMU 2 0 83 34 49 1-0 1-0 2W
Virginia 2 0 93 11 82 2-0 0-0 2W
California 1 1 45 63 -18 0-1 1-0 1W
Duke 2 0 48 30 18 1-0 1-0 2W
North Carolina 2 0 50 13 37 1-0 1-0 2W
Pittsburgh 2 0 71 21 50 2-0 0-0 2W
Boston College 1 1 43 55 -12 1-0 0-1 1W
Clemson 1 1 32 58 -26 1-0 0-1 1W
Louisville 1 1 97 54 43 1-0 0-1 1W
Georgia Tech 0 2 37 59 -22 0-2 0-0 2L
Florida State 1 1 58 44 14 1-1 0-0 1L
NC State 1 1 81 34 47 1-0 0-1 1W
Stanford 1 1 43 72 -29 1-1 0-0 1L
Syracuse 1 1 84 24 60 1-1 0-0 1L

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