Duke vs Virginia Prediction, Picks & Odds | 23 Oct 2026
Duke vs Virginia Predictions
Virginia are available at -128 when it comes to the Moneyline. Our prediction is that they’ll outscore Duke and there’s value available when it comes to these odds.
Get our primary Duke vs Virginia picks, built around our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Scroll down for a closer look at the reasoning behind the card.
Duke vs Virginia Preview
Duke face Virginia at Scott Stadium, with kickoff scheduled for 19:00 on Friday, October 23.
Duke Blue Devils suffered a second consecutive defeat when losing 24-20 in their previous game. This was at home to North Carolina Tar Heels at Wallace Wade Stadium.
Virginia Cavaliers have secured back-to-back home victories. Their last game was on the road and a 23-13 loss occurred against SMU Mustangs at Gerald J. Ford Stadium.
H2H: 5 Wins in Previous 7 H2H Matchups for UVA
Duke triumphed 27-20 (OT) when they last played Virginia. This head-to-head was played at Bank of America Stadium. In the past 7 games between the teams, Virginia have won five.
Quarterbacks
Best Bet
We’re keeping our pick simple and backing Virginia to win. They should be able to triumph in this college football battle and you can get them at a tempting -128.
Key stats supporting our main match prediction:
The CFB handicappers at Sportsgambler.com regularly track injury updates and pair that with current form. We also tap into a deep stats database to highlight the key numbers that help shape our picks.
UVA Moneyline Probability
According to the best betting apps, there’s a 56.2% chance that our pick is settled as a winner. Based on our in-depth research, our analysts calculate the actual probability to be 60-65%. The wager can be recommended for this precise reason.
Virginia are available at a range of odds against the spread. If you are looking for more juice, then check out the latest betting lines and choose from the available options.
Before placing a wager, see what betting offers are on the table. Our in-depth guide lists the top welcome bonuses right now.
Player Prop Picks
The odds for Beau Pribula (Virginia) to reach over 179.5 passing yards are -114. The line for QB Passing Yards looks attractive and we’re confident of securing a return.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Pick
Check out this same game parlay which starts with Virginia on the moneyline. We’ve also gone for Over 47.5 points and Beau Pribula (Virginia) to have Over 179.5 passing yards.
A same game parlay is a fantastic option for bettors who want to focus their wagering on a single football game. You can predict different outcomes and see their odds combined before going ahead and placing this tailored bet.
Correct Score Prediction
Duke vs Virginia Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
When you consider the latest Moneyline odds, you can find Virginia at -128 whereas Duke are +106. In the eyes of the leading sportsbooks, the home team are regarded as 56% likely to claim a victory.
1.5 is the spread and 47.5 is the total points line. There are many ways to wager on football including the Totals. Those that want to back Under 47.5 can find odds of -115 available.
College football bettors are spoilt for choice thanks to the huge selection of team props and game lines which are available for every matchup on the coupon. Head to the top sportsbooks and find the best value wagers.
Receiving Yards
Rushing Yards
Passing Yards
Virginia on Top in Recent Head-to-Heads at Scott Stadium
Virginia are 8-2 in their last 10 home games, scoring 34.20 points per contest and conceding 17.80.
Duke have six wins and four losses in the last 10 games away from home, averaging 32.50 points on offense and surrendering 29.20 on defense.
The most recent Scott Stadium meeting saw Duke claim a 27-20 win over Virginia. In the past 4 head-to-head meetings at Scott Stadium, Virginia have won every game.
| Last 10 Games | W-L | P | PF | PA | O47.5 | U47.5 | |
|---|---|---|---|---|---|---|---|
Virginia Home Stats |
8-2 | 52.00 | 34.20 | 17.80 | 5 | 5 | |
Duke Away Stats |
6-4 | 61.70 | 32.50 | 29.20 | 8 | 2 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O47.5 = Games Over 47.5 Points
- U47.5 = Games Under 47.5 Points
Latest regular season and playoff games stats.
Duke Blue Devils Stats
Virginia Cavaliers Stats
- 8 wins and 2 defeats in the last 10 games
- 6 wins and 4 defeats in the last 10 games on the road
- +1.5 Betting Line: Have covered the spread in 8 of the last 10 games
- +1.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road
- -1.5 Betting Line: Have covered the spread in 6 of the last 10 games
- -1.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games
- Game Totals: An average of 55.20 pts in the previous 10 games
- Game Totals on the Road: An average of 61.70 pts in the previous 10 games on the road
- Over 47.5: Covered in 6 of the previous 10 games
- Over 47.5 on the Road: Covered in 8 of the previous 10 games on the road
- Team Totals: Have scored an average of 34.00 pts and allowed 21.20 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 32.50 pts and allowed 29.20 pts in the last 10 games on the road
- Game Totals: An average of 44.90 pts in the previous 10 games
- Game Totals at Home: An average of 49.90 pts in the previous 10 home games
- Over 47.5: Covered in 3 of the previous 10 games
- Over 47.5 at Home: Covered in 4 of the previous 10 home games
- Team Totals: Have scored an average of 27.00 pts and allowed 17.90 pts in the last 10 games
- Team Totals at Home: Have scored an average of 31.40 pts and allowed 18.50 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Miami
|
6 | 0 | 291 | 84 | 207 | 3-0 | 3-0 | 6W |
North Carolina
|
4 | 2 | 141 | 115 | 26 | 1-1 | 3-1 | 2W |
Wake Forest
|
6 | 1 | 262 | 136 | 126 | 2-1 | 4-0 | 4W |
SMU
|
5 | 1 | 196 | 128 | 68 | 4-0 | 1-1 | 3W |
California
|
3 | 4 | 167 | 194 | -27 | 2-3 | 1-1 | 1L |
Louisville
|
4 | 3 | 271 | 192 | 79 | 3-1 | 1-2 | 2W |
Pittsburgh
|
5 | 2 | 230 | 115 | 115 | 4-1 | 1-1 | 2L |
Virginia Tech
|
5 | 2 | 260 | 148 | 112 | 3-1 | 2-1 | 1W |
Virginia
|
4 | 3 | 210 | 138 | 72 | 4-1 | 0-2 | 1L |
Duke
|
4 | 2 | 190 | 96 | 94 | 3-1 | 1-1 | 2L |
Boston College
|
3 | 3 | 122 | 138 | -16 | 3-1 | 0-2 | 1W |
NC State
|
3 | 3 | 198 | 166 | 32 | 3-1 | 0-2 | 1L |
Georgia Tech
|
2 | 4 | 160 | 163 | -3 | 2-2 | 0-2 | 1L |
Florida State
|
3 | 4 | 221 | 195 | 26 | 3-1 | 0-3 | 2L |
Stanford
|
3 | 4 | 128 | 256 | -128 | 3-1 | 0-3 | 1W |
Clemson
|
4 | 2 | 134 | 129 | 5 | 3-1 | 1-1 | 1W |
Syracuse
|
2 | 4 | 190 | 154 | 36 | 1-2 | 1-2 | 2L |
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Virginia Home Stats
Duke Away Stats
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