Memphis vs South Florida Prediction, Picks & Odds | 12 Nov 2026

Memphis vs South Florida Predictions

Best Bet

South Florida +3.5 @ -105

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We’re confident that South Florida can produce a strong performance against Memphis. Our prediction is that they’ll cover the spread of +3.5 and you can currently get -105.

We've identified our Best Bet for Memphis vs South Florida, alongside our Same Game Parlay and Correct Score Prediction. Each dedicated breakdown offers insight into the reasoning for the picks.

Memphis vs South Florida Preview

Memphis square off against South Florida at Raymond James Stadium, with kickoff scheduled for 20:00 on Thursday, November 12.

Memphis Tigers claimed a home victory in their previous game. A 49-22 triumph against Army Black Knights at Simmons Bank Liberty Stadium made it back-to-back wins.

South Florida Bulls have landed two home wins on the spin. It was a road defeat to East Carolina Pirates in their last game, losing 20-17 at Dowdy-Ficklen Stadium.

H2H: Memphis Have Enjoyed Upper Hand Over USF

Memphis triumphed 34-31 when they last played USF. This head-to-head was played at Simmons Bank Liberty Stadium. Memphis have a 100% win record when it comes to the previous 5 H2H meetings.

Best Bet

There’s a good opportunity to back South Florida against the spread considering the underdogs should perform well in this college football matchup. Snap up the -105 when it comes to them covering the +3.5.

Key stats supporting our main match prediction:

• The +3.5 line has been covered by South Florida in 8 of their last 10 games at home.
• The +3.5 line has been covered by South Florida in 4 of their last 5 games at home this season.
• The +3.5 line has been covered by South Florida in 3 consecutive games.
• The -3.5 line hasn’t been covered by Memphis in 3 of their last 5 games on the road.

We track all injuries that could impact each team before making our CFB picks. The form guide and latest stats also help the Sportsgambler.com team crunch the numbers ahead of the action.

USF +3.5 Probability

The best sportsbooks make it a 51.3% chance that our pick is settled as a winner. After careful examination, our analysts have this probability somewhere between 55-60%. It's why we think it’s worth placing this college wager.

A Bet Builder provides you with the chance to combine USF on the spread with other picks. For every additional selection, the odds are boosted.

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South Florida +3.5 @ -105 Bet Now

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Correct Score Prediction

Memphis 28 - 31 South Florida

For a fun bet, consider backing the Bulls to claim a 31-28 win. Although it’s a speculative wager, we are expecting things to be close between the two teams.

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Memphis vs South Florida Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Memphis are regarded as having a 64% chance of winning this college game according to the latest betting odds. The sportsbooks have priced them up at -179. For those wanting to back South Florida, you will find +146 about the underdogs.

The current spread is 3.5 and the total points line is 50.5. Football fans love the chance to get an alternative angle by going for a Total wager. Those expecting a low total can back Under 50.5 at -110.

You’ll find a great variety of team props and game lines for most college football showdowns. The best betting apps provide a strong mix of pre-game and in-game options to suit your betting style.

Moneyline

Memphis

-179

USF

+146

Point Spread

Memphis -3.5

-115

USF +3.5

-105

Total Points

Under 50.5

-110

Over 50.5

-110

USF Record Shows Nine Wins in Last Ten at Home

USF are 9-1 in their last 10 home games, scoring 42.20 points per contest and conceding 13.40.

Memphis have gone 5-5 across their last 10 games away from home, averaging 30.20 points on offense and surrendering 23.80 on defense.

The last Raymond James Stadium meeting saw Memphis beat USF 21-3.

Last 10 Games		W-L	P	PF	PA	O50.5	U50.5
South Florida Home Stats		9-1	55.60	42.20	13.40	6	4
Memphis Away Stats		5-5	54.00	30.20	23.80	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O50.5 = Games Over 50.5 Points
• U50.5 = Games Under 50.5 Points

Latest regular season and playoff games stats.

Memphis Tigers Stats

South Florida Stats

Moneyline

• 7 wins and 3 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 games on the road

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 8 wins and 2 defeats in the last 10 home games

Point Spread

• -3.5 Betting Line: Have covered the spread in 7 of the last 10 games
• -3.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road

Point Spread

• +3.5 Betting Line: Have covered the spread in 7 of the last 10 games
• +3.5 Betting Line at Home: Have covered the spread in 8 of the last 10 home games

Total Points

• Game Totals: An average of 58.80 pts in the previous 10 games
• Game Totals on the Road: An average of 54.00 pts in the previous 10 games on the road
• Over 50.5: Covered in 7 of the previous 10 games
• Over 50.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 34.50 pts and allowed 24.30 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 30.20 pts and allowed 23.80 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 40.30 pts in the previous 10 games
• Game Totals at Home: An average of 51.30 pts in the previous 10 home games
• Over 50.5: Covered in 3 of the previous 10 games
• Over 50.5 at Home: Covered in 5 of the previous 10 home games
• Team Totals: Have scored an average of 24.30 pts and allowed 16.00 pts in the last 10 games
• Team Totals at Home: Have scored an average of 36.90 pts and allowed 14.40 pts in the last 10 home games

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