Stanford vs Duke Prediction, Picks & Odds | 19 Sep 2026
College Football Betting Preview: Stanford vs Duke
Stanford battle Duke at Wallace Wade Stadium, with kickoff scheduled for 16:00 on Saturday, September 19.
We’re predicting that Duke will be superior to Stanford and that’s why we’re backing them at -10.5 on the spread. Take the -110 that the big favorites are able to cover this line.
Stanford Cardinal were beaten 45-6 at Stanford Stadium in their previous game, being turned over at home to Miami Hurricanes.
Duke Blue Devils won their last game 31-27, making it back-to-back successes. This was a road victory at Memorial Stadium against Illinois Fighting Illini.
Quarterbacks
Davis Warren
Walker Eget
Stanford vs Duke Prediction & Picks
Head into Stanford vs Duke with expert betting insights, including our main match prediction, expected scoreline, key player prop picks and a thoughtfully built bet builder.
Game Prediction
There’s everything to like about the -10.5 line that the favorites have to cover in this college football battle. Take the -110 and feel confident that Duke get the job done.
Our team of college football handicappers track current injuries closely. Combined with recent form, this helps us identify the best value odds. A data-led approach backed by key stats and the latest team news keeps our analysis sharp.
Key Stanford vs Duke stats:
Duke -10.5 Probability
When you look at the latest odds, our pick has a 52.4% chance of delivering a return. Our cappers think there’s a stronger chance of success and calculate the probability to be closer to 60%. That means we are regarding it as a value wager.
There’s regularly the option to sell points and that allows you to leverage a bigger potential return. Conversely, buying points will give you a less-risky wager but shorter odds.
Elevate your wagering experience with the latest free bets, promos and top betting offers listed in our comprehensive bonus guide.
Player Prop Picks
The odds for Walker Eget (Duke) to reach over 212.5 passing yards stand at -114. The line for QB Passing Yards looks attractive and we’re confident of securing a return.
The odds for Micah Ford (Duke) to record more than 72.5 rushing yards are -114. We believe it makes sense to stick with him on the Over and bettors can be confident in this Player Rushing Yards pick.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
We’ve compiled a same game parlay that includes Duke -10.5 on the spread, combined with Over 51.5 and Walker Eget (Duke) to have Over 212.5 passing yards.
A football same game parlay is a single event wager where you make predictions that are going to happen in a particular game. Should a bettor get these picks correct, then they can achieve a big return from a small stake.
Correct Score Prediction
20
-
38
Duke
There are stacks of correct score lines available and we’re looking at the Blue Devils to achieve a winning scoreline of 38-20 where a massive potential return is on the cards.
Stanford vs Duke Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Duke have short betting odds and they’re overwhelming -417 favorites for this college game. This means the sportsbooks give them a 81% chance of winning. The market suggests that Stanford are least likely to win at +320.
The spread currently stands at 10.5 and the total points line is 51.5. Having a bet on the Totals is one of the most popular football wagers. Those expecting a low total can back Under 51.5 at -118.
When it comes to college football, the top betting apps deliver a wide variety of game lines and team props. With so many options available, it’s worth taking your time to find the wager that fits your view of the matchup.
Receiving Yards
Rushing Yards
Passing Yards
Duke Have Collected Six Wins in Past Ten Home Games
Duke own a 6-4 mark in their past 10 home games, averaging 29.10 points scored and 26.30 points allowed.
Stanford have stumbled to ten straight defeats on the road. They have zero win and ten losses in the last 10 road games, scoring 16.20 points per matchup and conceding 36.00.
| Last 10 Games | W-L | P | PF | PA | O51.5 | U51.5 | |
|---|---|---|---|---|---|---|---|
 Duke Home Stats |
6-4 | 55.40 | 29.10 | 26.30 | 6 | 4 | |
 Stanford Away Stats |
0-10 | 52.20 | 16.20 | 36.00 | 4 | 6 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O51.5 = Games Over 51.5 Points
- U51.5 = Games Under 51.5 Points
Latest regular season and playoff games stats.
Stanford Cardinal Stats
Duke Blue Devils Stats
- 4 wins and 6 defeats in the last 10 games
- 0 wins and 10 defeats in the last 10 games on the road
- +10.5 Betting Line: Have covered the spread in 5 of the last 10 games
- +10.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road
- -10.5 Betting Line: Have covered the spread in 2 of the last 10 games
- -10.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games
- Game Totals: An average of 50.00 pts in the previous 10 games
- Game Totals on the Road: An average of 52.20 pts in the previous 10 games on the road
- Over 51.5: Covered in 4 of the previous 10 games
- Over 51.5 on the Road: Covered in 4 of the previous 10 games on the road
- Team Totals: Have scored an average of 19.60 pts and allowed 30.40 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 16.20 pts and allowed 36.00 pts in the last 10 games on the road
- Game Totals: An average of 60.20 pts in the previous 10 games
- Game Totals at Home: An average of 59.60 pts in the previous 10 home games
- Over 51.5: Covered in 6 of the previous 10 games
- Over 51.5 at Home: Covered in 7 of the previous 10 home games
- Team Totals: Have scored an average of 31.30 pts and allowed 28.90 pts in the last 10 games
- Team Totals at Home: Have scored an average of 31.00 pts and allowed 28.60 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Miami
|
2 | 0 | 122 | 13 | 109 | 1-0 | 1-0 | 2W |
Pittsburgh
|
3 | 0 | 98 | 34 | 64 | 3-0 | 0-0 | 3W |
SMU
|
2 | 0 | 83 | 34 | 49 | 1-0 | 1-0 | 2W |
Virginia
|
2 | 0 | 93 | 11 | 82 | 2-0 | 0-0 | 2W |
California
|
1 | 1 | 45 | 63 | -18 | 0-1 | 1-0 | 1W |
|
Duke
|
2 | 0 | 48 | 30 | 18 | 1-0 | 1-0 | 2W |
Louisville
|
1 | 1 | 97 | 54 | 43 | 1-0 | 0-1 | 1W |
Clemson
|
1 | 1 | 32 | 58 | -26 | 1-0 | 0-1 | 1W |
Boston College
|
1 | 1 | 43 | 55 | -12 | 1-0 | 0-1 | 1W |
Wake Forest
|
2 | 0 | 76 | 52 | 24 | 1-0 | 1-0 | 2W |
Virginia Tech
|
2 | 0 | 117 | 24 | 93 | 2-0 | 0-0 | 2W |
North Carolina
|
2 | 0 | 50 | 13 | 37 | 1-0 | 1-0 | 2W |
Georgia Tech
|
0 | 2 | 37 | 59 | -22 | 0-2 | 0-0 | 2L |
Florida State
|
1 | 1 | 58 | 44 | 14 | 1-1 | 0-0 | 1L |
NC State
|
1 | 1 | 81 | 34 | 47 | 1-0 | 0-1 | 1W |
|
Stanford
|
1 | 1 | 43 | 72 | -29 | 1-1 | 0-0 | 1L |
Syracuse
|
1 | 2 | 97 | 51 | 46 | 1-1 | 0-1 | 2L |
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