Vanderbilt vs Mississippi State Prediction, Picks & Odds | 07 Nov 2026

Vanderbilt vs Mississippi State Predictions

Best Bet

Over 48.5 Points @ -110

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Let’s go for Over 48.5 when Mississippi State face Vanderbilt. We think the line is too generous and we’re expecting the final total to be higher at -110.

We’ve locked in our preferred Vanderbilt vs Mississippi State wagers, including our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Check out the dedicated segments below for the full analysis of each pick.

Vanderbilt vs Mississippi State Preview

Vanderbilt face Mississippi State at Davis Wade Stadium, with kickoff scheduled for 16:15 on Saturday, November 7.

Vanderbilt Commodores have been defeated in their previous five games. On the road, they recently suffered a 34-17 loss against Kentucky Wildcats at Kroger Field.

Mississippi State Bulldogs have been defeated in their last four games. On the road, they recently suffered a 31-3 loss against Texas Longhorns at DKR-Texas Memorial Stadium.

H2H: 45-6 Win for MS State in Last H2H Clash

It was Mississippi State who came out on top when they last played Vanderbilt. At FirstBank Stadium, a 45-6 win was recorded.

Best Bet

The two teams should be able to accumulate enough points for our pick to win. We’re forecasting Over 48.5 and odds of -110 are available for this college football matchup.

Key stats supporting our main match prediction:

• The 48.5 line has been covered in the last 4 Vanderbilt games.
• The 48.5 line has been covered in 8 of the last 10 Vanderbilt games.
• The 48.5 line has been covered in 6 of the last 8 Vanderbilt games this season.
• The 48.5 line has been covered in 8 of the last 10 Mississippi State games at home.
• The 48.5 line has been covered in 16 of the last 20 Mississippi State games at home.

Our CFB picks always start with checking the latest team news and understanding how it might impact the game. From there, we dive into the most valuable stats to uncover the insights that matter most.

Over 48.5 Probability

According to the top sportsbooks, our pick has a 52.4% chance of delivering a return. After careful examination, our team calculate this probability to be closer to 60%. This is why we can recommend this college bet.

If you have a strong hunch for Overs but want to get bigger odds, consider the Result & Total lines. Get both predictions correct for a profitable return.

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Over 48.5 Points @ -110 Bet Now

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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Nov 5, 22:26). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Player Prop Picks

Top Pick: Jared Curtis Over 239.5 Passing Yards -114

The odds for Jared Curtis (Vanderbilt) to go accumulate over 239.5 passing yards stand at -114. We believe it makes sense to stick with him on the Over and bettors can be confident in this QB Passing Yards pick.

Latest Jared Curtis Player Prop Odds

Passing Yards

Over 239.5

-114

Under 239.5

-114

Rushing Yards

Over 19.5

-114

Under 19.5

-114

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Fluff Bothwell Over 91.5 Rushing Yards -114

Fluff Bothwell (Vanderbilt) is priced at -114 to go beyond 91.5 rushing yards. We’re confident in taking him to cover the Player Rushing Yards line and bettors can place this bet with confidence.

Latest Fluff Bothwell Player Prop Odds

Receiving Yards

Over 10.5

-114

Under 10.5

-114

Rushing Yards

Over 91.5

-114

Under 91.5

-114

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Vanderbilt 21 - 31 MS State

Should you want a wager that can land a big return, then look no further than the correct score lines. Bet on the Bulldogs to win 31-21 and leverage a massive payout if this happens.

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Vanderbilt vs Mississippi State Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Mississippi State are regarded as having a 60% chance of winning this college game according to the latest betting odds. The sportsbooks have priced them up at -147. The market suggests that Vanderbilt are least likely to win at +122.

The spread currently stands at 2.5 and the total points line is 48.5. Football bettors regularly enjoy the opportunity to wager on the Totals. If you fancy Over 48.5, this outcome can be backed at -110. 

Whether you are wagering pre-game or in-game on college football, the top betting apps let you feast on a wide range of team props and game lines. The selections are practically endless, and it’s awesome to have so many options at your fingertips.

Moneyline

Vanderbilt

+122

MS State

-147

Point Spread

Vanderbilt +2.5

-100

MS State -2.5

-122

Total Points

Under 48.5

-110

Over 48.5

-110

Receiving Yards

Junior Sherrill (Vanderbilt)

Over 89.5

-114

Under 89.5

-114

Anthony Evans III (MS State)

Over 59.5

-114

Under 59.5

-114

Cole Spence (Vanderbilt)

Over 24.5

-114

Under 24.5

-114

Sedrick Alexander (Vanderbilt)

Over 16.5

-114

Under 16.5

-114

Fluff Bothwell (MS State)

Over 10.5

-114

Under 10.5

-114

Rushing Yards

Fluff Bothwell (MS State)

Over 91.5

-114

Under 91.5

-114

Sedrick Alexander (Vanderbilt)

Over 34.5

-114

Under 34.5

-114

Jared Curtis (Vanderbilt)

Over 19.5

-114

Under 19.5

-114

Mississippi State Sitting on Six Losses in Their Previous Ten at Home

Mississippi State own a 4-6 mark in their past 10 home games, putting up 34.40 points on average and giving up 29.10.

Vanderbilt have taken three consecutive losses away from home. They have four wins and six losses in the last 10 road games, averaging 24.50 points scored and 23.90 points allowed.

In their most recent matchup at Davis Wade Stadium, Mississippi State got the better of Vanderbilt 24-17.

Last 10 Games		W-L	P	PF	PA	O48.5	U48.5
Mississippi State Home Stats		4-6	63.50	34.40	29.10	8	2
Vanderbilt Away Stats		4-6	48.40	24.50	23.90	5	5

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O48.5 = Games Over 48.5 Points
• U48.5 = Games Under 48.5 Points

Latest regular season and playoff games stats.

Vanderbilt Commodores Stats

Mississippi State Bulldogs Stats

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 games on the road

Moneyline

• 4 wins and 6 defeats in the last 10 games
• 3 wins and 7 defeats in the last 10 home games

Point Spread

• +2.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +2.5 Betting Line on the Road: Have covered the spread in 4 of the last 10 games on the road

Point Spread

• -2.5 Betting Line: Have covered the spread in 4 of the last 10 games
• -2.5 Betting Line at Home: Have covered the spread in 3 of the last 10 home games

Total Points

• Game Totals: An average of 55.40 pts in the previous 10 games
• Game Totals on the Road: An average of 48.40 pts in the previous 10 games on the road
• Over 48.5: Covered in 8 of the previous 10 games
• Over 48.5 on the Road: Covered in 5 of the previous 10 games on the road
• Team Totals: Have scored an average of 25.40 pts and allowed 30.00 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 24.50 pts and allowed 23.90 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 56.70 pts in the previous 10 games
• Game Totals at Home: An average of 64.40 pts in the previous 10 home games
• Over 48.5: Covered in 7 of the previous 10 games
• Over 48.5 at Home: Covered in 8 of the previous 10 home games
• Team Totals: Have scored an average of 26.10 pts and allowed 30.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 31.00 pts and allowed 33.40 pts in the last 10 home games

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