Clemson vs Syracuse Prediction, Picks & Odds | 07 Nov 2026
Clemson vs Syracuse Predictions
Syracuse look a great play at +2.5 on the spread. They could beat Clemson and the -112 about this selection makes lots of appeal.
Our betting picks for Clemson vs Syracuse cover our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Read on to discover the specific reasoning behind the card.
Clemson vs Syracuse Preview
Clemson face Syracuse at JMA Wireless Dome, with kickoff scheduled for 12:00 on Saturday, November 7.
Clemson Tigers have won back-to-back road games. A 36-24 triumph recently occurred at Doak Campbell Stadium when playing Florida State Seminoles.
Syracuse Orange made it back-to-back wins in their last game. Landing a 30-27 home victory against SMU Mustangs at JMA Wireless Dome.
H2H: 5 Clemson Wins in Previous 6 H2H Encounters
These two teams last met at Memorial Stadium, with Syracuse claiming the win. Beating Clemson by a 34-21 scoreline. The past 6 games between the teams have seen Clemson win five times.
Quarterbacks
Tait Reynolds
Steve Angeli
Best Bet
Our pick is that Syracuse will cover the line and prove to be competitive. It’s currently set at +2.5 for this college football showdown and that makes plenty of appeal, with -112 available.
Key stats supporting our main match prediction:
Our CFB predictions are rooted in solid team news and up-to-date form for each team. We also dig deep to uncover the most relevant stats that help guide and strengthen our picks.
Syracuse +2.5 Probability
If you go by the top betting apps, there’s a 52.9% chance that our pick is settled as a winner. Our cappers think there’s a stronger chance of success and calculate the probability to be 55-60%. The wager can be recommended for this precise reason.
If you are looking for bigger odds, then you are able to move the line. Choose from a wide range of options and get rewarded if your selection exceeds expectations.
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Player Prop Picks
The odds for Tait Reynolds (Clemson) to record fewer than 204.5 passing yards stand at -114. There’s a strong case for choosing him to fall short of the required line in the QB Passing Yards market.
You can place a bet on Umari Hatcher (Clemson) at -114 to record fewer than 75.5 receiving yards. Considering all factors, we’re confident he’ll fall short of the Player Receiving Yards line.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Pick
We’ve compiled a same game parlay that includes Syracuse +2.5 on the spread, combined with Over 49.5 and Tait Reynolds (Clemson) to have Under 204.5 passing yards.
A same game parlay allows bettors to place a multiple wager on the same football game. You can go through the available betting lines and cherry-pick the outcomes that you think will happen. The odds for each selection are then combined together.
Correct Score Prediction
28
-
30
Syracuse
We’re expecting this to be a close matchup and we’ll take Syracuse to win 30-28. This is available at massive odds for those that want to have a speculative wager.
Clemson vs Syracuse Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
There are betting odds of +112 about Syracuse winning, with Clemson currently available at -133. In the eyes of the leading sportsbooks, the home team are regarded as 47% likely to claim a victory.
There is a spread of 2.5 and total points has a line of 49.5. A Total wager is always available and can often provide value selections. If you’re going for Under 49.5, this outcome can be backed at -106.
Make sure to explore all angles before placing your college football bets. The top sportsbooks offer a wide range of game lines and team props and it’s all about finding a wager which matches your prediction of the matchup.
Receiving Yards
Rushing Yards
Passing Yards
Clemson Have Won Last Three Head-to-Head Meetings at JMA Wireless Dome
Syracuse have four wins and six losses in the last 10 games at home, putting up 27.10 points per matchup and giving up 25.80.
Clemson have gone 7-3 across their last 10 games games on the road, scoring 27.60 points per contest and conceding 23.10.
Clemson beat Syracuse 31-14 when the teams last met at JMA Wireless Dome. Clemson have taken all 3 of the recent head-to-head meetings at JMA Wireless Dome.
| Last 10 Games | W-L | P | PF | PA | O49.5 | U49.5 | |
|---|---|---|---|---|---|---|---|
 Syracuse Home Stats |
4-6 | 52.90 | 27.10 | 25.80 | 4 | 6 | |
 Clemson Away Stats |
7-3 | 50.70 | 27.60 | 23.10 | 5 | 5 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O49.5 = Games Over 49.5 Points
- U49.5 = Games Under 49.5 Points
Latest regular season and playoff games stats.
Clemson Tigers Stats
Syracuse Orange Stats
- 6 wins and 4 defeats in the last 10 games
- 7 wins and 3 defeats in the last 10 games on the road
- -2.5 Betting Line: Have covered the spread in 6 of the last 10 games
- -2.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road
- +2.5 Betting Line: Have covered the spread in 4 of the last 10 games
- +2.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games
- Game Totals: An average of 43.30 pts in the previous 10 games
- Game Totals on the Road: An average of 50.70 pts in the previous 10 games on the road
- Over 49.5: Covered in 3 of the previous 10 games
- Over 49.5 on the Road: Covered in 5 of the previous 10 games on the road
- Team Totals: Have scored an average of 22.40 pts and allowed 20.90 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 27.60 pts and allowed 23.10 pts in the last 10 games on the road
- Game Totals: An average of 58.50 pts in the previous 10 games
- Game Totals at Home: An average of 52.90 pts in the previous 10 home games
- Over 49.5: Covered in 7 of the previous 10 games
- Over 49.5 at Home: Covered in 4 of the previous 10 home games
- Team Totals: Have scored an average of 27.00 pts and allowed 31.50 pts in the last 10 games
- Team Totals at Home: Have scored an average of 27.10 pts and allowed 25.80 pts in the last 10 home games
| Atlantic Coast | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
Miami
|
8 | 0 | 381 | 142 | 239 | 4-0 | 4-0 | 8W |
Wake Forest
|
7 | 1 | 313 | 143 | 170 | 3-1 | 4-0 | 5W |
SMU
|
6 | 2 | 282 | 178 | 104 | 5-0 | 1-2 | 1L |
Louisville
|
5 | 3 | 323 | 216 | 107 | 4-1 | 1-2 | 3W |
Duke
|
6 | 2 | 256 | 114 | 142 | 4-1 | 2-1 | 2W |
Virginia Tech
|
6 | 2 | 280 | 164 | 116 | 3-1 | 3-1 | 2W |
|
Clemson
|
5 | 3 | 186 | 173 | 13 | 3-2 | 2-1 | 1W |
Pittsburgh
|
6 | 3 | 287 | 178 | 109 | 5-1 | 1-2 | 1W |
Boston College
|
4 | 4 | 173 | 212 | -39 | 3-1 | 1-3 | 1L |
NC State
|
4 | 4 | 257 | 207 | 50 | 4-1 | 0-3 | 1W |
North Carolina
|
4 | 4 | 206 | 184 | 22 | 1-3 | 3-1 | 2L |
|
Syracuse
|
4 | 4 | 251 | 211 | 40 | 2-2 | 2-2 | 2W |
Stanford
|
4 | 5 | 183 | 336 | -153 | 4-1 | 0-4 | 1L |
Virginia
|
4 | 5 | 233 | 208 | 25 | 4-2 | 0-3 | 3L |
California
|
3 | 6 | 197 | 284 | -87 | 2-3 | 1-3 | 3L |
Florida State
|
3 | 5 | 245 | 231 | 14 | 3-2 | 0-3 | 3L |
Georgia Tech
|
2 | 6 | 198 | 246 | -48 | 2-3 | 0-3 | 3L |
Virginia Tech
SMU
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