Northwestern Wildcats
American Football NCAAF Spartan Stadium Sat 17 Oct 12:00
Michigan State Spartans (MSU)
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Northwestern vs Michigan State Predictions

Best Bet

Michigan State +7.5 @ -115

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Michigan State to Make it a Close Battle

Our best bet is Michigan State at +7.5 on the spread. A win or narrow defeat against Northwestern would mean our pick at -115 lands a return.

We've selected our preferred Northwestern vs Michigan State picks, including our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Dive deep into the analytical breakdown of each play below.

Northwestern vs Michigan State Preview

Northwestern face Michigan State at Spartan Stadium, with kickoff scheduled for 12:00 on Saturday, October 17.

Northwestern Wildcats claimed a home victory in their previous game. A 45-14 triumph against Ball State Cardinals at Ryan Field made it back-to-back wins.

Michigan State Spartans have lost on their last four outings. In a recent home game at Spartan Stadium, they were turned over 38-37 (OT) by Illinois Fighting Illini.

H2H: Michigan State 38-21 Winners When Teams Last Met

The scoreline was 38-21 in favor of Michigan State when they last played Northwestern, with the matchup taking place at Ryan Field. Michigan State have won on the past 3 times these teams have gone H2H.

Quarterbacks

Best Bet

Our best wager is for Michigan State to cover the spread. +7.5 at odds of -115 look more than generous and we’re happy to back this college football pick.

Key stats supporting our main match prediction:

  • The +7.5 line has been covered by Michigan State in 4 of their last 5 games at home.
  • The +7.5 line has been covered by Michigan State in 3 of their last 4 games at home this season.
  • The -7.5 line hasn’t been covered by Northwestern in 9 consecutive games on the road.
  • The -7.5 line hasn’t been covered by Northwestern in 18 of their last 20 games on the road.
  • The +7.5 line has been covered by Michigan State in 3 consecutive games against Northwestern.

We closely track recent form and look for patterns that may impact the outcome. The same goes for injuries to key players. When combined with the most relevant stats, this gives us a strong foundation for accurate CFB picks.

Michigan State +7.5 Probability

The top betting apps make it a 53.5% chance that our pick is settled as a winner. However, we think that the probability is close to 60% taking all factors into consideration. This is why we can recommend this college wager.

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Michigan State +7.5 @ -115 Bet Now BetMGM logo
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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Oct 15, 18:25). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.
Published 18:25, 15 October 2026

Player Prop Picks

Top Pick: Alessio Milivojevic Over 191.5 Passing Yards -114 BetMGM logo

Alessio Milivojevic (Michigan State) is priced at -114 to rack up over 191.5 passing yards. We can place a QB Passing Yards bet with confidence, as we expect him to cover the line.

Latest Alessio Milivojevic Player Prop Odds

Rodney Bullard Jr. Over 42.5 Receiving Yards -114 BetMGM logo

The odds for Rodney Bullard Jr. (Michigan State) to go over 42.5 receiving yards are -114. We're confident in him covering the Player Receiving Yards line and hitting our Over bet.

Latest Rodney Bullard Jr. Player Prop Odds

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Same Game Parlay Pick

Spread Michigan State +7.5
Totals Over 48.5
Passing Yards Alessio Milivojevic Over 191.5

Try out our same game parlay pick which starts with Michigan State +7.5. We’ve also gone for Over 48.5 points and Alessio Milivojevic (Michigan State) to go Over 191.5 passing yards.

A football same game parlay is a single event wager where you make predictions that are going to happen in a particular game. Should a bettor get these picks correct, then they can achieve a big return from a small stake.

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Northwestern Northwestern logo 28 - 27 Michigan State logo Michigan State

We’ll throw a dart when it comes to the Wildcats landing a 28-27 win. This correct score pick is available at huge odds and could be an entertaining bet to place.

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Northwestern vs Michigan State Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Latest Moneyline Odds Suggest Northwestern Victory

The sportsbooks’ betting odds have Northwestern as -286 favorites for this college game, implying that they are 74% likely to win. If you’re looking for an alternative angle, Michigan State are trading at +230.

The spread is currently 7.5, with the total points line at 48.5. A wager on the Totals allows football bettors to use the latest data to good effect. Those that want to back Under 48.5 can find odds of -104 available.

The top sportsbooks cover every college football matchup with a great mix of game lines and team props. Whether you prefer to bet before kickoff or during the action, make sure to explore all available options.

Player Odds

Receiving Yards

Griffin Wilde (Northwestern)
Over 79.5
-114
Under 79.5
-114
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Rodney Bullard Jr. (MSU)
Over 42.5
-114
Under 42.5
-114
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Drew Wagner (Northwestern)
Over 36.5
-114
Under 36.5
-114
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Rushing Yards

Jaziun Patterson (MSU)
Over 79.5
-114
Under 79.5
-114
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Caleb Komolafe (Northwestern)
Over 69.5
-114
Under 69.5
-114
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Aidan Chiles (Northwestern)
Over 19.5
-114
Under 19.5
-114
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Passing Yards

Aidan Chiles (Northwestern)
Over 221.5
-114
Under 221.5
-114
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Alessio Milivojevic (MSU)
Over 191.5
-114
Under 191.5
-114
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Live market odds and lines updated regularly. All odds subject to change. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
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Spartan Stadium
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Michigan State Have Five Wins From Past Ten Home Game

Michigan State have a 5-5 record in their last 10 home games, putting up 26.40 points on average and giving up 26.30.

Northwestern have come up short in four consecutive away outings. They have three wins and seven losses in the last 10 games on the road, putting up 18.20 points per contest and giving up 27.90.

In their last matchup at Spartan Stadium, Michigan State came out on top 29-20 against Northwestern.

Last 10 Games W-L P PF PA O48.5 U48.5
Michigan State logo Michigan State Home Stats 5-5 52.70 26.40 26.30 6 4
Northwestern logo Northwestern Away Stats 3-7 46.10 18.20 27.90 5 5
  • W-L = Wins-Losses
  • P = Avg. Points
  • PF = Avg. Points For
  • PA = Avg. Points Against
  • O48.5 = Games Over 48.5 Points
  • U48.5 = Games Under 48.5 Points
Last 5 & H2H
Team Stats

Latest regular season and playoff games stats.

Northwestern Wildcats logo Northwestern Wildcats Stats
Michigan State Spartans logo Michigan State Spartans Stats
Moneyline
  • 6 wins and 4 defeats in the last 10 games
  • 3 wins and 7 defeats in the last 10 games on the road
Moneyline
  • 3 wins and 7 defeats in the last 10 games
  • 5 wins and 5 defeats in the last 10 home games
Point Spread
Point Spread
Total Points
Total Points
NCAAF Standings Select Season
Big Ten W L PF PA N. Pts Home Away Strk
Indiana 6 0 241 71 170 4-0 2-0 6W
Ohio State 5 1 256 79 177 4-0 1-1 4W
UCLA 5 0 196 90 106 2-0 3-0 5W
Wisconsin 4 1 158 83 75 3-0 1-1 4W
USC 6 1 255 176 79 4-1 2-0 2W
Iowa 5 1 186 87 99 3-1 2-0 1W
Nebraska 5 1 235 91 144 4-1 1-0 1L
Minnesota 4 2 173 131 42 3-1 1-1 1L
Purdue 3 3 193 188 5 2-2 1-1 2W
Northwestern 4 1 177 81 96 4-0 0-1 2W
Oregon 3 2 205 110 95 2-1 1-1 1L
Illinois 3 3 191 167 24 2-2 1-1 1W
Maryland 2 4 168 196 -28 1-2 1-2 4L
Michigan State 2 4 128 154 -26 2-2 0-2 4L
Michigan 3 2 115 79 36 3-1 0-1 2L
Washington 3 3 157 133 24 3-2 0-1 3L
Penn State 3 3 183 111 72 2-2 1-1 3L
Rutgers 1 4 150 161 -11 1-3 0-1 1L

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