South Carolina vs Alabama Prediction, Picks & Odds | 26 Sep 2026
College Football Betting Preview: South Carolina vs Alabama
South Carolina square off against Alabama at Bryant-Denny Stadium, with kickoff scheduled for 19:00 on Saturday, September 26.
Let’s go for Alabama at a generous -12.5 on the spread. We really like this pick and are able to get odds of -110 that they beat South Carolina by a big margin.
South Carolina Gamecocks lost when they last took to the field. At Williams-Brice Stadium, they were turned over 41-34 at home to Mississippi State Bulldogs.
Alabama Crimson Tide won their last game 50-36, making it three victories on the bounce. This was a home win at Bryant-Denny Stadium against Florida State Seminoles.
Head-to-Head Statistics
Alabama beat South Carolina when the teams last met. It was a 29-22 scoreline at Williams-Brice Stadium. Alabama have won all of the past 3 H2H meetings.
Quarterbacks
LaNorris Sellers
Keelon Russell
South Carolina vs Alabama Prediction & Picks
We bring you the complete South Carolina vs Alabama betting insight, including our top match prediction, correct score forecast, player prop advice and a ready-made bet builder.
Game Prediction
We’re predicting that this could be a one-sided college football affair. Our pick is to therefore take Alabama at -110 to cover an appealing -12.5 line on the spread.
Our CFB predictions are rooted in solid team news and up-to-date form for each team. We also dig deep to uncover the most relevant stats that help guide and strengthen our picks.
Key South Carolina vs Alabama stats:
Bama -12.5 Probability
The best sportsbooks make it a 52.4% chance that our pick is settled as a winner. Our experts think there’s a stronger chance of success and calculate the probability to be closer to 60%. It's therefore regarded as a value wager.
Bigger prices can be secured for bettors who are prepared to move the line. The odds increase according to how much risk you are prepared to have with your wager.
Get rewarded when bet. Check our latest guide featuring top-rated free bets, promotions and sign-up bonuses.
Player Prop Picks
The odds for LaNorris Sellers (South Carolina) to have less than 226.5 passing yards are -114. He could struggle to reach the QB Passing Yards line, making this prop bet highly appealing.
Nyck Harbor (South Carolina) is available at -114 to finish with fewer than 37.5 receiving yards. The line looks too high and we’re confident he’ll fall short of the Player Receiving Yards total.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
We’ve loaded up a same game parlay with the combined picks of Alabama -12.5, Under 54.5 and LaNorris Sellers (South Carolina) to go Under 226.5 passing yards.
We recommend a same game parlay as it’s a great way of betting on a single event. Many football bettors like to create a personalised wager which reflects their predictions for how a game is going to play out.
Correct Score Prediction
13
-
34
Alabama
Should you want to go for a selection at massive odds, head to the correct score lines where the Crimson Tide can be backed speculatively to achieve a 34-13 victory.
South Carolina vs Alabama Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The sportsbooks are taking no chances with their Moneyline odds of -526 about Alabama which reflects they have a 84% chance of winning this college game. For those wanting to oppose the market leader, you can get +385 about South Carolina.
12.5 is the spread and 54.5 is the total points line. There is no denying the popularity of wagering on the Totals. If you fancy Under 54.5, then the odds are -114.
If you’re betting on college football, we recommend heading to the top betting apps and scanning through the many team props and game lines. There’s a chance to wager pre-game and in-game.
Receiving Yards
Rushing Yards
Passing Yards
Alabama Racking Up the Home Wins
Alabama have stacked up three straight victories at Bryant-Denny Stadium. They have a 9-1 record in their last 10 home games, averaging 40.10 points on offense and surrendering 14.00 on defense.
South Carolina have suffered five consecutive road defeats. They have a 4-6 record in their last 10 road games, putting up 22.70 points per contest and giving up 19.40.
Alabama beat South Carolina 27-25 in their most recent meeting at Bryant-Denny Stadium.
| Last 10 Games | W-L | P | PF | PA | O54.5 | U54.5 | |
|---|---|---|---|---|---|---|---|
 Alabama Home Stats |
9-1 | 54.10 | 40.10 | 14.00 | 5 | 5 | |
 South Carolina Away Stats |
4-6 | 42.10 | 22.70 | 19.40 | 1 | 9 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O54.5 = Games Over 54.5 Points
- U54.5 = Games Under 54.5 Points
Latest regular season and playoff games stats.
South Carolina Gamecocks Stats
Alabama Crimson Tide Stats
- 3 wins and 7 defeats in the last 10 games
- 4 wins and 6 defeats in the last 10 games on the road
- +12.5 Betting Line: Have covered the spread in 7 of the last 10 games
- +12.5 Betting Line on the Road: Have covered the spread in 9 of the last 10 games on the road
- -12.5 Betting Line: Have covered the spread in 4 of the last 10 games
- -12.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games
- Game Totals: An average of 50.50 pts in the previous 10 games
- Game Totals on the Road: An average of 42.10 pts in the previous 10 games on the road
- Over 54.5: Covered in 4 of the previous 10 games
- Over 54.5 on the Road: Covered in 1 of the previous 10 games on the road
- Team Totals: Have scored an average of 28.40 pts and allowed 22.10 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 22.70 pts and allowed 19.40 pts in the last 10 games on the road
- Game Totals: An average of 51.60 pts in the previous 10 games
- Game Totals at Home: An average of 53.40 pts in the previous 10 home games
- Over 54.5: Covered in 5 of the previous 10 games
- Over 54.5 at Home: Covered in 5 of the previous 10 home games
- Team Totals: Have scored an average of 31.10 pts and allowed 20.50 pts in the last 10 games
- Team Totals at Home: Have scored an average of 38.00 pts and allowed 15.40 pts in the last 10 home games
| Southeastern | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
|
Alabama
|
3 | 0 | 143 | 63 | 80 | 2-0 | 1-0 | 3W |
Florida
|
3 | 0 | 162 | 63 | 99 | 2-0 | 1-0 | 3W |
Georgia
|
3 | 0 | 178 | 40 | 138 | 2-0 | 1-0 | 3W |
Mississippi State
|
3 | 0 | 141 | 60 | 81 | 1-0 | 2-0 | 3W |
Ole Miss
|
3 | 0 | 114 | 71 | 43 | 3-0 | 0-0 | 3W |
Kentucky
|
2 | 1 | 93 | 79 | 14 | 1-1 | 1-0 | 1W |
Missouri
|
3 | 0 | 119 | 52 | 67 | 2-0 | 1-0 | 3W |
Tennessee
|
3 | 0 | 143 | 42 | 101 | 2-0 | 1-0 | 3W |
Texas
|
3 | 0 | 113 | 36 | 77 | 3-0 | 0-0 | 3W |
Vanderbilt
|
3 | 0 | 98 | 66 | 32 | 3-0 | 0-0 | 3W |
Oklahoma
|
2 | 1 | 75 | 23 | 52 | 2-0 | 0-1 | 1W |
Auburn
|
2 | 1 | 99 | 68 | 31 | 2-1 | 0-0 | 1L |
LSU
|
2 | 1 | 120 | 56 | 64 | 2-0 | 0-1 | 1L |
|
South Carolina
|
2 | 1 | 136 | 50 | 86 | 2-1 | 0-0 | 1L |
Texas A&M
|
2 | 1 | 119 | 51 | 68 | 2-1 | 0-0 | 1L |
Arkansas
|
1 | 2 | 58 | 102 | -44 | 1-1 | 0-1 | 2L |
Army
Temple
Predictions
19:00 - Fri 25 Sep
NCAAF
Navy
UAB
Predictions
20:00 - Fri 25 Sep
NCAAF
Northwestern
Indiana
Predictions
22:30 - Fri 25 Sep
NCAAF
Clemson
California
Predictions
12:00 - Sat 26 Sep
NCAAF
Virginia Tech
Boston College
Predictions
12:00 - Sat 26 Sep
NCAAF
Wake Forest
Louisville
Predictions
12:00 - Sat 26 Sep
NCAAF
Illinois
Ohio State
Predictions
12:00 - Sat 26 Sep
NCAAF
San Diego State
Toledo
Predictions
12:00 - Sat 26 Sep
NCAAF
Texas
Tennessee
Predictions
12:00 - Sat 26 Sep
NCAAF
Sam Houston
Texas Tech
Predictions
12:00 - Sat 26 Sep
NCAAF
Colorado
Baylor
Predictions
12:00 - Sat 26 Sep
NCAAF
Colorado State
UTSA
Predictions
12:00 - Sat 26 Sep
NCAAF
UNLV
Akron
Predictions
12:00 - Sat 26 Sep
NCAAF
Ball State
Kent State
Predictions
12:45 - Sat 26 Sep
NCAAF
South Alabama
Kentucky
Predictions
13:30 - Sat 26 Sep
NCAAF
UCLA
Maryland
Predictions
Brisbane Bullets
Illawarra Hawks
Predictions
12:00 - Fri 25 Sep
UEFA Nations League
Georgia
Northern Ireland
Predictions
12:00 - Fri 25 Sep
UEFA Nations League
Armenia
Latvia
Predictions
12:30 - Fri 25 Sep
BBL
Trier
Telekom Bonn
Predictions
14:00 - Fri 25 Sep
BBL
Hamburg Towers
Chemnitz
Predictions
14:00 - Fri 25 Sep
BBL
Mitteldeutscher
Jena
Predictions
Where to Bet on American Football Games
Where to Trade American Football Games
Availability varies by jurisdiction. Some platforms featured may not be accessible in your location. Please check the relevant review page for details.