Illinois vs Ohio State Prediction, Picks & Odds | 26 Sep 2026
College Football Betting Preview: Illinois vs Ohio State
Illinois square off against Ohio State at Ohio Stadium, with kickoff scheduled for 12:00 on Saturday, September 26.
We’re not sure that Ohio State and Illinois will reach a certain points threshold. Our prediction is to take the -115 that there are Under 54.5 points.
Illinois Fighting Illini won their previous game which was at home. It was a 48-10 triumph at Memorial Stadium against Southern Illinois.
Ohio State Buckeyes won their last game 59-3, making it back-to-back home wins. This was recorded at Ohio Stadium against Kent State Golden Flashes.
Head-to-Head Statistics
The last matchup between Ohio State and Illini saw the former win. It was a 34-16 scoreline at Memorial Stadium.
Quarterbacks
Katin Houser
Julian Sayin
Illinois vs Ohio State Prediction & Picks
Explore our best Illinois vs Ohio State picks, including our main match prediction, correct score forecast, player performance props and a bet builder ready to use.
Game Prediction
Under 54.5 points could be on the money for this college football battle. Our pick is based on a low-scoring game and the odds of -115 looks like a value wager.
The CFB handicappers at Sportsgambler.com always keep close tabs on team news as it develops. We also rely on recent form and key stats to help shape our picks and guide the final call.
Key Illinois vs Ohio State stats:
Under 54.5 Probability
According to the best betting apps, our pick has a 53.5% chance of winning. In the opinion of our cappers, there’s actually a probability of success closer to 60%. It is therefore regarded as a value bet.
We recommend moving the line if you want more juice from your Total bet. If you’re going Under, then consider a slightly riskier wager which has a bigger payout.
Before placing your bets, explore the latest betting offers. Our comprehensive guide features a wide range of welcome bonuses to choose from.
Player Prop Picks
The odds for Katin Houser (Illini) to have less than 180.5 passing yards are -114. We're confident he’ll fall short of the QB Passing Yards line, so we're backing the Under.
The odds for Jeremiah Smith (Illini) to end with fewer than 121.5 receiving yards are -114. Several factors suggest he will fall short of the Player Receiving Yards line, making this an appealing wager.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Picks
Get in the game with a same game parlay. Our picks are Under 54.5 on the total, Ohio State to cover the -27.5 spread and Katin Houser (Illinois) to have Under 180.5 passing yards.
The same game parlay option is fantastic for football bettors wanting a personalised multi-leg wager on the same game. It’s especially good if you have a strong opinion on the likely outcomes and the odds for each selection are combined.
Correct Score Prediction
9
-
41
Ohio State
There are stacks of correct score lines available and we’re looking at the Buckeyes to achieve a winning scoreline of 41-9 where a massive potential return is on the cards.
Illinois vs Ohio State Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Ohio State are massive -5000 favorites. They are regarded as 98% likely to win this college game judging by the sportsbooks’ latest Moneyline odds. If you’re looking for an alternative angle, Illinois are trading at +1600.
27.5 is where the spread lies, with total points being 54.5 right now. There are many ways to wager on football including the Totals. If you want to bet Under 54.5, there are odds of -115.
College football bettors are spoilt for choice thanks to the huge selection of team props and game lines which are available for every matchup on the coupon. Head to the top sportsbooks and find the best value wagers.
Jeremiah Smith is the market leader to score a touchdown at anytime and you can get -238. There is the chance to back the favorite to grab the first TD at odds of +330.
Touchdown
Receiving Yards
Passing Yards
Can Ohio State Stay Hot at Home?
Ohio State are 10-0 in their last 10 home games, putting up 44.80 points per contest and giving up 7.50.
Illini have gone 5-5 across their last 10 games away from home, averaging 25.60 points on offense and surrendering 32.00 on defense.
| Last 10 Games | W-L | P | PF | PA | O54.5 | U54.5 | |
|---|---|---|---|---|---|---|---|
 Ohio State Home Stats |
10-0 | 52.30 | 44.80 | 7.50 | 5 | 5 | |
 Illinois Away Stats |
5-5 | 57.60 | 25.60 | 32.00 | 7 | 3 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O54.5 = Games Over 54.5 Points
- U54.5 = Games Under 54.5 Points
Latest regular season and playoff games stats.
Illinois Fighting Illini Stats
Ohio State Buckeyes Stats
- 6 wins and 4 defeats in the last 10 games
- 5 wins and 5 defeats in the last 10 games on the road
- +27.5 Betting Line: Have covered the spread in the last 10 games
- +27.5 Betting Line on the Road: Have covered the spread in 8 of the last 10 games on the road
- -27.5 Betting Line: Have covered the spread in 4 of the last 10 games
- -27.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games
- Game Totals: An average of 50.40 pts in the previous 10 games
- Game Totals on the Road: An average of 57.60 pts in the previous 10 games on the road
- Over 54.5: Covered in 5 of the previous 10 games
- Over 54.5 on the Road: Covered in 7 of the previous 10 games on the road
- Team Totals: Have scored an average of 27.70 pts and allowed 22.70 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 25.60 pts and allowed 32.00 pts in the last 10 games on the road
- Game Totals: An average of 47.00 pts in the previous 10 games
- Game Totals at Home: An average of 50.40 pts in the previous 10 home games
- Over 54.5: Covered in 3 of the previous 10 games
- Over 54.5 at Home: Covered in 4 of the previous 10 home games
- Team Totals: Have scored an average of 35.10 pts and allowed 11.90 pts in the last 10 games
- Team Totals at Home: Have scored an average of 41.60 pts and allowed 8.80 pts in the last 10 home games
| Big Ten | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
UCLA
|
3 | 0 | 125 | 72 | 53 | 2-0 | 1-0 | 3W |
USC
|
4 | 0 | 172 | 91 | 81 | 3-0 | 1-0 | 4W |
Indiana
|
3 | 0 | 145 | 16 | 129 | 3-0 | 0-0 | 3W |
Maryland
|
2 | 1 | 126 | 49 | 77 | 1-1 | 1-0 | 1L |
Wisconsin
|
2 | 1 | 103 | 60 | 43 | 2-0 | 0-1 | 2W |
Oregon
|
2 | 1 | 149 | 66 | 83 | 2-0 | 0-1 | 1W |
|
Ohio State
|
2 | 1 | 138 | 30 | 108 | 2-0 | 0-1 | 1W |
Minnesota
|
2 | 1 | 113 | 52 | 61 | 2-1 | 0-0 | 1W |
Michigan State
|
2 | 1 | 75 | 54 | 21 | 2-0 | 0-1 | 1L |
|
Illinois
|
2 | 1 | 117 | 64 | 53 | 2-1 | 0-0 | 1W |
Iowa
|
3 | 0 | 111 | 13 | 98 | 3-0 | 0-0 | 3W |
Washington
|
3 | 0 | 88 | 40 | 48 | 3-0 | 0-0 | 3W |
Penn State
|
3 | 0 | 127 | 22 | 105 | 2-0 | 1-0 | 3W |
Northwestern
|
2 | 0 | 75 | 25 | 50 | 2-0 | 0-0 | 2W |
Nebraska
|
3 | 0 | 139 | 35 | 104 | 3-0 | 0-0 | 3W |
Michigan
|
3 | 0 | 82 | 39 | 43 | 3-0 | 0-0 | 3W |
Purdue
|
1 | 2 | 118 | 109 | 9 | 1-1 | 0-1 | 2L |
Rutgers
|
0 | 3 | 77 | 107 | -30 | 0-2 | 0-1 | 3L |
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