Cardinals vs Rams Prediction, Picks & Odds | 18 Oct 2026

Cardinals vs Rams Predictions

Best Bet

Cardinals +12.5 @ -110

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The Cardinals look capable of avoiding a heavy defeat against the Rams and we’re happy to bet them against the spread. The underdogs can comfortably cover +12.5 and this can be backed at -110.

Get our expert Cardinals vs Rams predictions, including our Best Bet, Player Props, Same Game Parlay and Correct Score Pick. Explore each section for the complete analysis.

Cardinals vs Rams Preview

The Arizona Cardinals go up against the Los Angeles Rams at SoFi Stadium, with kickoff scheduled for 16:05 on Sunday, October 18.

Arizona Cardinals have suffered four straight defeats, recently being beaten at home by Detroit Lions 45-21 at State Farm Stadium. The Cardinals generated 327 total yards, made up of 271 passing and 56 rushing yards. The offense moved the chains 20 times and struck for 3 touchdowns.

Los Angeles Rams lost when they last took to the field. At SoFi Stadium, they were turned over 37-34 at home to Buffalo Bills. The Rams put up 454 total yards, made up of 377 through the air and 77 on the ground. They moved the chains 33 times and struck for 5 touchdowns.

H2H: Rams Have 8 Wins in Past 10 on H2H

The scoreline was 37-20 in favor of the Rams when they last played the Cards, with the matchup taking place at SoFi Stadium. The past 10 H2H games have seen the Rams land eight wins.

Quarterbacks

Jacoby Brissett

237.5 Passing Yards

Over -114

Under -114

Matthew Stafford

279.5 Passing Yards

Over -114

Under -114

Best Bet

There’s a lot to like about the Cardinals +12.5 when they play this NFL matchup. You can get odds of -110 and we need the underdogs to avoid a big loss.

Key stats supporting our main match prediction:

• The +12.5 line has been covered by Cardinals in 3 consecutive games on the road.
• The +12.5 line has been covered by Cardinals in 15 of their last 20 games on the road.
• The +12.5 line has been covered by Cardinals in 6 of their last 10 games on the road.
• The -12.5 line hasn’t been covered by Rams in 8 of their last 10 games.
• The -12.5 line hasn’t been covered by Rams in 4 of their last 5 games this season.
• The -12.5 line hasn’t been covered by Rams in 3 consecutive games.

We only publish our NFL predictions once we’ve got a clear and confident read on team news and the latest form. We also stay sharp by digging into the most valuable stats to support every pick we make.

Cards +12.5 Probability

Based on the odds from the top NFL betting sites, there’s a 52.4% likelihood of our pick delivering a return. However, our cappers think that the probability sits between 55-60% taking all factors into consideration. This is why we can recommend this bet.

If you want to secure a bigger possible payout on your wager, there’s the possibility to move the line. Take a look at the various odds and see which spread you think will be covered.

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Cardinals +12.5 @ -110 Bet Now

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Player Prop Picks

Top Pick: Matthew Stafford Under 279.5 Passing Yards -114

The odds for Matthew Stafford (Rams) to finish with fewer than 279.5 passing yards stand at -114. He’s not guaranteed to cover the QB Passing Yards line and we’re happy to take this bet.

Latest Matthew Stafford Player Prop Odds

Touchdown

Anytime

+1500

First

+8000

Passing Yards

Over 279.5

-114

Under 279.5

-114

Rushing Yards

Over 1.5

+112

Under 1.5

-147

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Blake Corum Under 42.5 Rushing Yards -114

Blake Corum (Cards) is available at -114 to have less than 42.5 rushing yards. The line looks too high and we’re confident he’ll fall short of the Player Rushing Yards total.

Latest Blake Corum Player Prop Odds

Touchdown

Anytime

+140

First

+1000

Receiving Yards

Over 6.5

-114

Under 6.5

-114

Rushing Yards

Over 42.5

-114

Under 42.5

-114

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Correct Score Prediction

Cardinals 23 - 34 Rams

The Rams might be able to claim a victory and we’re siding with a 34-23 scoreline in their favor. A small stake can provide a big return and there are monster odds available.

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Cardinals vs Rams Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

The favorites are 89% likely to win according to the sportsbooks’ latest Moneyline odds, with Los Angeles Rams priced at -833 to triumph in this game. If you’re looking for an alternative angle, Arizona Cardinals are trading at +560.

The spread is 12.5 and the total points line is currently 51.5. There is no denying the popularity of betting on the Totals. Those that want to back Under 51.5 can find odds of -105 available.

Consider every angle when placing your National Football League wagers. The top betting apps have a huge selection of game lines and team props and it’s all about finding a bet which matches your prediction of the game.

Moneyline

Cardinals

+560

Rams

-833

Point Spread

Cardinals +12.5

-110

Rams -12.5

-110

Total Points

Under 51.5

-105

Over 51.5

-115

Kyren Williams is the market leader at +420 to be the First TD Scorer. Should you think he will score the final touchdown, then a similar price can be found.

Touchdown

Kyren Williams (Rams)

First TD

+420

Anytime TD

-222

Puka Nacua (Rams)

First TD

+500

Anytime TD

-169

Davante Adams (Rams)

First TD

+650

Anytime TD

-125

Jeremiyah Love (Cardinals)

First TD

+950

Anytime TD

+115

Tyler Allgeier (Cardinals)

First TD

+950

Anytime TD

+115

Blake Corum (Rams)

First TD

+1000

Anytime TD

+140

Trey McBride (Cardinals)

First TD

+1400

Anytime TD

+150

Tyler Higbee (Rams)

First TD

+1600

Anytime TD

+270

Michael Wilson (Cardinals)

First TD

+1700

Anytime TD

+200

Colby Parkinson (Rams)

First TD

+1900

Anytime TD

+340

Bam Knight (Cardinals)

First TD

+2500

Anytime TD

+460

Kendrick Bourne (Cardinals)

First TD

+3500

Anytime TD

+550

Davis Allen (Rams)

First TD

+3500

Anytime TD

+800

CJ Daniels (Rams)

First TD

+4000

Anytime TD

+900

Tutu Atwell (Rams)

First TD

+4000

Anytime TD

+900

Jalen Brooks (Cardinals)

First TD

+4000

Anytime TD

+600

Jacoby Brissett (Cardinals)

First TD

+5000

Anytime TD

+800

Konata Mumpfield (Rams)

First TD

+5500

Anytime TD

+1100

Jordan Whittington (Rams)

First TD

+6000

Anytime TD

+1200

Elijah Higgins (Cardinals)

First TD

+6000

Anytime TD

+1000

Teagan Quitoriano (Cardinals)

First TD

+7000

Anytime TD

+1000

Max Klare (Rams)

First TD

+7500

Anytime TD

+1700

Matthew Stafford (Rams)

First TD

+8000

Anytime TD

+1500

Alex Bachman (Rams)

First TD

+10000

Anytime TD

+2700

Devin Duvernay (Cardinals)

First TD

+10000

Anytime TD

+2200

Simi Fehoko (Cardinals)

First TD

+10000

Anytime TD

+3500

Reggie Virgil (Cardinals)

First TD

+10000

Anytime TD

+2000

Dean Connors (Rams)

First TD

+10000

Anytime TD

+3300

Shawn Bowman (Cardinals)

First TD

+10000

Anytime TD

+3000

Receiving Yards

Puka Nacua (Rams)

Over 92.5

-114

Under 92.5

-114

Trey McBride (Cardinals)

Over 64.5

-114

Under 64.5

-114

Michael Wilson (Cardinals)

Over 58.5

-114

Under 58.5

-114

Davante Adams (Rams)

Over 57.5

-114

Under 57.5

-114

Kendrick Bourne (Cardinals)

Over 35.5

-114

Under 35.5

-114

Tyler Higbee (Rams)

Over 32.5

-114

Under 32.5

-114

Jalen Brooks (Cardinals)

Over 20.5

-114

Under 20.5

-114

Kyren Williams (Rams)

Over 19.5

-114

Under 19.5

-114

Colby Parkinson (Rams)

Over 13.5

-114

Under 13.5

-114

Elijah Higgins (Cardinals)

Over 12.5

-114

Under 12.5

-114

Jeremiyah Love (Cardinals)

Over 10.5

-114

Under 10.5

-114

Tyler Allgeier (Cardinals)

Over 8.5

-114

Under 8.5

-114

Davis Allen (Rams)

Over 7.5

-114

Under 7.5

-114

Blake Corum (Rams)

Over 6.5

-114

Under 6.5

-114

Rushing Yards

Kyren Williams (Rams)

Over 69.5

-114

Under 69.5

-114

Tyler Allgeier (Cardinals)

Over 46.5

-114

Under 46.5

-114

Jeremiyah Love (Cardinals)

Over 45.5

-114

Under 45.5

-114

Blake Corum (Rams)

Over 42.5

-114

Under 42.5

-114

Jacoby Brissett (Cardinals)

Over 6.5

-114

Under 6.5

-114

Matthew Stafford (Rams)

Over 1.5

+112

Under 1.5

-147

Passing Yards

Matthew Stafford (Rams)

Over 279.5

-114

Under 279.5

-114

Jacoby Brissett (Cardinals)

Over 237.5

-114

Under 237.5

-114

Rams Have Bossed Recent Head-to-Heads at SoFi Stadium

The Rams own a 8-2 mark in their past 10 home games, putting up 29.30 points per contest and giving up 18.80.

The Cards have a 2-8 record in their last 10 games away from home, putting up 22.70 points on average and giving up 31.20.

The Rams defeated the Cards 37-20 the last time they played at SoFi Stadium. In the past 7 head-to-head meetings at SoFi Stadium, the Rams have won five while the Cards have two victories.

Last 10 Games		W-L	P	PF	PA	O51.5	U51.5
Rams Home Stats		8-2	48.10	29.30	18.80	3	7
Cardinals Away Stats		2-8	53.90	22.70	31.20	6	4

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O51.5 = Games Over 51.5 Points
• U51.5 = Games Under 51.5 Points

Latest regular season and playoff games stats.

Arizona Cardinals Stats

Los Angeles Rams Stats

Moneyline

• 1 win and 9 defeats in the last 10 games
• 2 wins and 8 defeats in the last 10 games on the road

Moneyline

• 5 wins and 5 defeats in the last 10 games
• 7 wins and 3 defeats in the last 10 home games

Point Spread

• +12.5 Betting Line: Have covered the spread in 4 of the last 10 games
• +12.5 Betting Line on the Road: Have covered the spread in 6 of the last 10 games on the road

Point Spread

• -12.5 Betting Line: Have covered the spread in 2 of the last 10 games
• -12.5 Betting Line at Home: Have covered the spread in 4 of the last 10 home games

Total Points

• Game Totals: An average of 54.50 pts in the previous 10 games
• Game Totals on the Road: An average of 53.90 pts in the previous 10 games on the road
• Over 51.5: Covered in 6 of the previous 10 games
• Over 51.5 on the Road: Covered in 6 of the previous 10 games on the road
• Team Totals: Have scored an average of 19.80 pts and allowed 34.70 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 22.70 pts and allowed 31.20 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 50.70 pts in the previous 10 games
• Game Totals at Home: An average of 49.20 pts in the previous 10 home games
• Over 51.5: Covered in 5 of the previous 10 games
• Over 51.5 at Home: Covered in 3 of the previous 10 home games
• Team Totals: Have scored an average of 26.10 pts and allowed 24.60 pts in the last 10 games
• Team Totals at Home: Have scored an average of 28.60 pts and allowed 20.60 pts in the last 10 home games

Game Stats

Last 10 Games

• Total Yards: Gained 299.70 Yds. Allowed 391.20 Yds
• Rushing Yards: Gained 83.40 Yds. Allowed 144.00 Yds
• Passing Yards: Gained 216.30 Yds. Allowed 247.20 Yds
• Total Touchdowns: Scored 2.20 TD. Allowed 4.30 TD
• Rushing Touchdowns: Scored 0.00 TD. Allowed 0.80 TD
• Passing Touchdowns: Scored 1.00 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 18.30. Allowed 23.50
• Total Turnovers: Committed 1.10. Committed by opponents 0.90
• Total Penalties: Committed 6.20. Committed by opponents 5.00
• Penalty Yards: Lost 53.10 Yds. Gained 38.20 Yds

Game Stats

Last 10 Games

• Total Yards: Gained 411.00 Yds. Allowed 323.40 Yds
• Rushing Yards: Gained 118.30 Yds. Allowed 125.80 Yds
• Passing Yards: Gained 292.70 Yds. Allowed 197.60 Yds
• Total Touchdowns: Scored 3.10 TD. Allowed 2.80 TD
• Rushing Touchdowns: Scored 0.30 TD. Allowed 0.40 TD
• Passing Touchdowns: Scored 0.90 TD. Allowed 0.60 TD
• Total 1st Downs: Picked up 23.30. Allowed 19.10
• Total Turnovers: Committed 1.30. Committed by opponents 1.20
• Total Penalties: Committed 6.40. Committed by opponents 5.90
• Penalty Yards: Lost 54.10 Yds. Gained 44.40 Yds

Last 10 Games on the Road

• Total Yards: Gained 334.60 Yds. Allowed 358.60 Yds
• Rushing Yards: Gained 95.60 Yds. Allowed 128.00 Yds
• Passing Yards: Gained 239.00 Yds. Allowed 230.60 Yds
• Total Touchdowns: Scored 2.60 TD. Allowed 3.70 TD
• Rushing Touchdowns: Scored 0.30 TD. Allowed 0.90 TD
• Passing Touchdowns: Scored 1.50 TD. Allowed 1.40 TD
• Total 1st Downs: Picked up 21.10. Allowed 21.60
• Total Turnovers: Committed 1.20. Committed by opponents 1.30
• Total Penalties: Committed 5.70. Committed by opponents 5.30
• Penalty Yards: Lost 52.70 Yds. Gained 43.00 Yds

Last 10 Home Games

• Total Yards: Gained 407.70 Yds. Allowed 328.10 Yds
• Rushing Yards: Gained 120.40 Yds. Allowed 108.30 Yds
• Passing Yards: Gained 287.30 Yds. Allowed 219.80 Yds
• Total Touchdowns: Scored 3.70 TD. Allowed 2.00 TD
• Rushing Touchdowns: Scored 0.50 TD. Allowed 0.30 TD
• Passing Touchdowns: Scored 2.10 TD. Allowed 1.00 TD
• Total 1st Downs: Picked up 23.90. Allowed 19.10
• Total Turnovers: Committed 0.90. Committed by opponents 1.70
• Total Penalties: Committed 5.20. Committed by opponents 6.00
• Penalty Yards: Lost 41.10 Yds. Gained 44.50 Yds

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