Oklahoma State vs Houston Prediction, Picks & Odds | 17 Oct 2026
Oklahoma State vs Houston Predictions
Go for Under at -110. It might be defenses on top when Houston clash with Oklahoma State, with the 62.5 points line looking on the high side when it comes to the totals.
Get our top Oklahoma State vs Houston betting recommendations, featuring our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Read on for detailed analysis of each pick.
Oklahoma State vs Houston Preview
Oklahoma State face Houston at TDECU Stadium, with kickoff scheduled for 19:30 on Saturday, October 17.
Oklahoma State Cowboys made it four consecutive wins after a 42-28 home success over UCF Knights at Boone Pickens Stadium.
Houston Cougars won last time out by a 35-16 scoreline. On the road against Kansas State Wildcats at Bill Snyder Family Stadium, they made it three wins on the spin.
H2H: Teams’ Last Matchup Saw 39-17 Houston Win
It was Houston who came out on top when they last played Oklahoma State. At Boone Pickens Stadium, a 39-17 win was recorded.
Quarterbacks
Drew Mestemaker
Conner Weigman
Best Bet
We’re confident about the number of points to be scored when the teams take to the field in this college football battle. Therefore, the pick is Under 62.5 points which is available at -110.
Key stats supporting our main match prediction:
Our CFB predictions are built after tracking the latest team news and reviewing recent form. We also dive into stats, which often serve as a solid barometer for how the action might unfold.
Under 62.5 Probability
Based on the odds from the top sportsbooks, our pick has a 52.4% chance of winning. However, our analysts have this figure between 55-60% based on their in-depth research. It is therefore regarded as a value bet.
We recommend moving the line if you want more juice from your Total bet. If you’re going Under, then consider a slightly riskier wager which has a bigger payout.
Get the most from your next wager. Check our expert guide filled with the best free bets and top bonus offers.
Player Prop Picks
Conner Weigman (Houston) can be backed at -114 to finish with fewer than 255.5 passing yards. He may fall short of the QB Passing Yards line, making this prop bet a strong pick.
Caleb Hawkins (Houston) is priced at -114 to have less than 92.5 rushing yards. He may fall short of the Player Rushing Yards line, making this prop bet a strong pick.
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Same Game Parlay Pick
Get in the game with a same game parlay. Our picks are Under 62.5 on the total, Houston to cover the -4.5 spread and Conner Weigman (Houston) to go Under 255.5 passing yards.
We recommend a same game parlay as it’s a great way of betting on a single event. Many football bettors like to create a personalised wager which reflects their predictions for how a game is going to play out.
Correct Score Prediction
21
-
34
Houston
There are some huge returns lying in wait if you can get the correct score right. With this in mind, we’ll have a play on the Coogs to enjoy a 34-21 winning scoreline.
Oklahoma State vs Houston Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
The sportsbooks’ betting odds have Houston as -185 favorites for this college game, implying that they are 65% likely to win. Oklahoma State are trading at bigger odds than their opponents and they can be backed at +152.
The spread is 4.5 and the total points line is currently 62.5. A Total wager is always available and can often provide value selections. Those that want to back Under 62.5 can find odds of -110 available.
There’s no shortage of betting opportunities when it comes to college football. The best betting apps offer a wide variety of team props and game lines for each game, so be sure to explore both the pre-game and in-game markets before making your pick.
Receiving Yards
Rushing Yards
Passing Yards
Houston Keep Cashing In at Home
Houston have reeled off three straight victories at TDECU Stadium. They have a 6-4 record in their last 10 home games, averaging 30.10 points scored and 20.80 points allowed.
Oklahoma State have gone 1-9 across their last 10 road games, putting up 14.30 points on average and giving up 38.30.
The previous meeting at TDECU Stadium saw Oklahoma State defeat Houston 43-30.
| Last 10 Games | W-L | P | PF | PA | O62.5 | U62.5 | |
|---|---|---|---|---|---|---|---|
 Houston Home Stats |
6-4 | 50.90 | 30.10 | 20.80 | 2 | 8 | |
 Oklahoma State Away Stats |
1-9 | 52.60 | 14.30 | 38.30 | 3 | 7 | |
- W-L = Wins-Losses
- P = Avg. Points
- PF = Avg. Points For
- PA = Avg. Points Against
- O62.5 = Games Over 62.5 Points
- U62.5 = Games Under 62.5 Points
Latest regular season and playoff games stats.
Oklahoma State Cowboys Stats
Houston Cougars Stats
- 4 wins and 6 defeats in the last 10 games
- 1 win and 9 defeats in the last 10 games on the road
- +4.5 Betting Line: Have covered the spread in 5 of the last 10 games
- +4.5 Betting Line on the Road: Have covered the spread in 2 of the last 10 games on the road
- -4.5 Betting Line: Have covered the spread in 6 of the last 10 games
- -4.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
- Game Totals: An average of 48.30 pts in the previous 10 games
- Game Totals on the Road: An average of 52.60 pts in the previous 10 games on the road
- Over 62.5: Covered in 3 of the previous 10 games
- Over 62.5 on the Road: Covered in 3 of the previous 10 games on the road
- Team Totals: Have scored an average of 24.50 pts and allowed 23.80 pts in the last 10 games
- Team Totals on the Road: Have scored an average of 14.30 pts and allowed 38.30 pts in the last 10 games on the road
- Game Totals: An average of 57.10 pts in the previous 10 games
- Game Totals at Home: An average of 55.20 pts in the previous 10 home games
- Over 62.5: Covered in 3 of the previous 10 games
- Over 62.5 at Home: Covered in 3 of the previous 10 home games
- Team Totals: Have scored an average of 35.30 pts and allowed 21.80 pts in the last 10 games
- Team Totals at Home: Have scored an average of 32.90 pts and allowed 22.30 pts in the last 10 home games
| Big 12 | W | L | PF | PA | N. Pts | Home | Away | Strk |
|---|---|---|---|---|---|---|---|---|
BYU
|
5 | 0 | 173 | 67 | 106 | 3-0 | 2-0 | 5W |
Texas Tech
|
5 | 0 | 174 | 81 | 93 | 3-0 | 2-0 | 5W |
Utah
|
5 | 0 | 214 | 65 | 149 | 4-0 | 1-0 | 5W |
Baylor
|
4 | 1 | 174 | 71 | 103 | 3-0 | 1-1 | 4W |
|
Oklahoma State
|
4 | 1 | 191 | 107 | 84 | 3-0 | 1-1 | 4W |
Arizona
|
5 | 1 | 214 | 114 | 100 | 3-0 | 2-1 | 4W |
|
Houston
|
5 | 1 | 240 | 115 | 125 | 3-0 | 2-1 | 3W |
Cincinnati
|
4 | 1 | 169 | 116 | 53 | 4-0 | 0-1 | 1L |
Arizona State
|
3 | 2 | 163 | 139 | 24 | 2-1 | 1-1 | 1W |
Iowa State
|
3 | 3 | 178 | 130 | 48 | 3-1 | 0-2 | 1L |
UCF
|
3 | 3 | 190 | 130 | 60 | 3-0 | 0-3 | 2L |
Kansas State
|
3 | 2 | 178 | 96 | 82 | 3-1 | 0-1 | 2L |
West Virginia
|
3 | 3 | 218 | 196 | 22 | 2-2 | 1-1 | 3L |
Colorado
|
2 | 3 | 93 | 127 | -34 | 1-1 | 1-2 | 3L |
Kansas
|
2 | 3 | 168 | 109 | 59 | 2-2 | 0-1 | 1L |
TCU
|
2 | 3 | 127 | 67 | 60 | 2-2 | 0-1 | 2L |
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